Hypersensitivity myocarditis and hypersensitivity coronary syndrome (Kounis syndrome)

Kounis, George N.; Soufras, George D.; Kouni, Sophia A.; Kounis, Nicholas G.

doi:10.1016/j.ajem.2009.02.025

Cited by 15 publications

(13 citation statements)

References 2 publications

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“…Cardiac enzymes level may be normal. [ 8 9 ] These cases have a normal myocardial perfusion scan, normal coronary angiogram, and positive ergonovine test. [ 8 ] The explanation for this type would be endothelial dysfunction or microvascular angina.…”

Section: Discussionmentioning

confidence: 99%

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Kounis syndrome: A rare case

Sunder

Mohanty

Singh

2020

J Family Med Prim Care

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Section: Discussionmentioning

confidence: 99%

“…In Type II, there is angiographic evidence of coronary artery disease during an acute allergic reaction. [ 8 9 ] This type includes patients with pre-existing atheromatous disease and an acute allergic episode induces plaque erosion or rupture manifesting as an acute myocardial infarction. [ 8 10 11 ]…”

Section: Discussionmentioning

confidence: 99%

Kounis syndrome: A rare case

Sunder

Mohanty

Singh

2020

J Family Med Prim Care

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“…The mechanism responsible for this type would be endothelial dysfunction or microvascular angina (7). In type 2, patients have underlying coronary artery disease, and chest pain occurs during an acute allergic reaction (8). An acute allergic episode can induce plaque erosion or rupture manifesting as an acute myocardial infarction (2,9).…”

Section: Discussionmentioning

confidence: 99%

Kounis Syndrome as a Result of Anaphylactic Reaction to Gold Dust: A Case Report

Bozan¹,

Kalkan²,

Atiş³

et al. 2019

eamr

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Kounis syndrome (KS) is described as the provocation of an acute coronary syndrome through activation of mast cells resulting in allergy, hypersensitivity, anaphylaxis, or anaphylactoid reaction. The case is here presented of a patient who developed KS with retrosternal chest pain and ST-segment elevation myocardial infarction 30 minutes after the ingestion of gold dust. A 40-year-old male without a history of allergy or atopy was admitted to the emergency room with complaints of red, itchy skin, chest pain, and shortness of breath 30 minutes after exposure to gold dust. Arterial blood pressure was 129/72 mmHg, pulse rate was 94 bpm, and oxygen saturation was 98%. On physical examination, urticarial lesions were observed on the anterior chest wall without uvula edema and pulmonary bronchospasm. Electrocardiogram (ECG) showed ST elevation in the V1-V6 and aVL leads. High sensitivity Troponin I level was measured as 12.1 ng/L (reference=0-19.8 ng/L), and the Troponin I levels increased to 229.7 ng/L two hours later. KS was considered because of the findings of chest pain, urticaria on the body, and lack of cardiac disorder. KS should be kept in mind in cases that present with allergic reactions together with chest pain following exposure to agents to which the immune system may be allergic. Cardiac enzymes can either be normal or elevated in these patients. ECG usually has ST, and the T wave changes.

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“…The characteristic pain of acute cardiac event can be masked by generalized aches and pain due to multiple stings. This can be due to the Kounis syndrome, also known as allergic angina or allergic myocardial infarction, is characterized by allergic reactions, coronary artery spasm and chest pain (5,6).It is not possible to identify the exact mechanism of myocardial involvement as both Type 1 hypersensitivity and direct toxic effects of the venoms are equally possible. Further investigation to find out the exact mechanism is technically and practically difficult in our setting.…”

Section: Discussionmentioning

confidence: 99%

Giant Asian honeybee stings induced acute myocarditis: a case report

Dinamithra

Sivansuthan

2013

Anuradhapura Med. J.

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Hymenopterid stings and subsequent allergic reactions including fatal anaphylaxis are a common indication for emergency department visits worldwide. Less commonly, multiple wasp stings can result in multi-system involvement ranging from intravascular hemolysis, rhabdomyolysis, acute renal failure, cardiac involvement, hepatic dysfunction and occasionally thrombocytopenia and coagulopathy. Here we report one case of multiple Giant Asian honey bee stings induced myocarditis

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Hypersensitivity myocarditis and hypersensitivity coronary syndrome (Kounis syndrome)

Cited by 15 publications

References 2 publications

Kounis syndrome: A rare case

Kounis syndrome: A rare case

Kounis Syndrome as a Result of Anaphylactic Reaction to Gold Dust: A Case Report

Giant Asian honeybee stings induced acute myocarditis: a case report

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