Hypocholesterolaemic effect of Bengal gram: a long-term study in man.

Mathur, K. S.; Khan, M. A.; Sharma, Rakesh

doi:10.1136/bmj.1.5583.30

Cited by 119 publications

(25 citation statements)

References 4 publications

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“…The former observation suggests that a diet high in fat will favour the production of small (i.e. LDL-forming) VLDL, and it is interesting to note that legumes are particularly effective at reducing cholesterol levels when the background diet is high in fat (Mathur et al 1968). If there is a component in legumes that can alter the secretion of VLDL in favour of large particles it has not yet been identified.…”

Section: Reduced Synthesis Of Ldlmentioning

confidence: 99%

The Influence of Legume Seeds on Human Plasma Lipid Concentrations

Kingman

1991

Nutr. Res. Rev.

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Section: Reduced Synthesis Of Ldlmentioning

confidence: 99%

The Influence of Legume Seeds on Human Plasma Lipid Concentrations

Kingman

1991

Nutr. Res. Rev.

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“…There were no changes in plasma cholesterol concentrations. Other sources of dietary fiber have been shown to be effective in lowering plasma lipid levels in both man and animals (23)(24)(25)(26)(27)(28)(29). Keys and co-workers demonstrated that legumes and citrus pectin lowered plasma cholesterol levels in man (28,55).…”

Section: Discussionmentioning

confidence: 99%

“…In Western countries, the average daily fiber intake is only one-fifth of what it was in the midnineteenth century (12). The crude fiber content of the present American diet is estimated to be 2-5 glday, whereas [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] glday is reported in more primitive cultures (13).…”

Section: Introductionmentioning

confidence: 99%

“…Studies with the addition of bran fiber have been largely negative in man, but some lowering of serum cholesterol levels has occurred with dietary supplements ofpectin, lignin, and various gums (23)(24)(25)(26)(27)(28)(29). In a variety of animals, a hypocholesterolemic effect has been reported in some but not all with the feeding of oats, wheat straw, rice bran, soy bran, alfalfa, and various mucilaginous materials (30)(31)(32)(33)(34).…”

Section: Introductionmentioning

confidence: 99%

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The Interaction of Dietary Fibers and Cholesterol upon the Plasma Lipids and Lipoproteins, Sterol Balance, and Bowel Function in Human Subjects

Raymond¹,

Connor²,

Lin³

et al. 1977

J. Clin. Invest.

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A B S T R A C T To identify any metabolic effects of dietary fiber upon cholesterol metabolism in man, six adult volunteer subjects were fed eucaloric cholesterolfree formula diets, with and without added dietary fiber for two 4-wk periods. A large quantity of dietary fiber was fed, some 60 g of plant cell wall material (or 16 g of crude fiber) derived from corn, beans, bran, pectin, and purified cellulose. This provided about five times the fiber intake of the typical American diet. The addition offiber to the cholesterol-free diet did not change either the plasma cholesterol level (171+21 mg/dl, SEM, to 167+18) or the triglyceride (103±39 to 93±27 mg/dl). The excretion of both endogenous neutral steroids and bile acids were unchanged with fiber (505±41 to 636 ±75 mg/day and 194±23 to 266±47 mg/day, respectively). However, total fecal steroid excretion was increased 699±29 to 902±64 mg/day, P < 0.025). With fiber, intestinal transit time was decreased (59±9 to 35±8 h, P < 0.005), and both the wet and dry stool weights were greatly increased.A second group of six subjects was fed similar diets containing 1,000 mg cholesterol derived from egg yolk. The addition of fiber to the 1,000-mg cholesterol diet did not alter either plasma cholesterol level (233±26 to 223±36 mg/dl) or triglyceride (102±19 to 83±11 mg/ dl). The excretion of endogenous neutral steroids (618 ±84 to 571±59 mg/day), of bile acids (423±122 to 401 ±89 mg/day), and of total fecal steroids (1,041±175 to 972±+111 mg/day) were unchanged by fiber. The absorption of dietary cholesterol was not altered when

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“…Consumption of large quantities of natural fiber have been associated with a hypocholesterolealc effect. Saponin in chick diets (Griminger and Fisher, 1958) and chick peas in human diets (Mathur et al, 1968) decreased serum cholester ol concentrations.…”

Section: Fibersmentioning

confidence: 99%

Influence of meal pattern and dietary fat on cholesterol metabolism in adult rats recovering from undernutrition

Carlson

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Hypocholesterolaemic effect of Bengal gram: a long-term study in man.

Cited by 119 publications

References 4 publications

The Influence of Legume Seeds on Human Plasma Lipid Concentrations

The Influence of Legume Seeds on Human Plasma Lipid Concentrations

The Interaction of Dietary Fibers and Cholesterol upon the Plasma Lipids and Lipoproteins, Sterol Balance, and Bowel Function in Human Subjects

Influence of meal pattern and dietary fat on cholesterol metabolism in adult rats recovering from undernutrition

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