Hypodontia: Prevalence and pattern amongst the living Druze population – A Near Eastern genetic isolate

Dental Anomalies in Consanguineous Marriage: A Clinical-Radiological Study

“…Patients with a history of any type of syndrome were excluded from the study. 17 , 18 , 19 Patients were classified into 2 groups according to their parents’ consanguineous marriage status. The individuals born from consanguineous marriage constituted the study group, and the individuals born from nonconsanguineous marriage constituted the control group.…”

“…16 Developmental dental anomalies (DDAs) can occur in several different contexts (eg, as isolated findings, as part of a syndrome), be related to different underlying conditions (eg, familial, idiopathic, consanguineous marriage), and be affected by several different factors (eg, genetic factors, environmental conditions, etc.). 17 , 18 , 19 , 20 DDAs can be divided into 4 types, with a given anomaly being classified as 1 of these: number, size, erupted, or altered dental morphology. 16 Various DDA types are quite common in clinical practice and can be diagnosed with the aid of clinical and radiological examination.…”

“…Although the relationship between consanguineous marriage and systemic diseases has been highlighted in many studies, 8 , 9 , 10 , 11 , 13 there are relatively few of these studies in the field of dentistry. 4 , 17 , 18 , 22 , 23 , 24 Previous research has investigated the relationship between consanguineous marriage and specific conditions such as hyperdontia, hypodontia, and aggressive periodontitis. 4 , 17 , 23 However, the effect of consanguineous marriage on the DDAs has not been extensively studied.…”

“… 4 , 17 , 18 , 22 , 23 , 24 Previous research has investigated the relationship between consanguineous marriage and specific conditions such as hyperdontia, hypodontia, and aggressive periodontitis. 4 , 17 , 23 However, the effect of consanguineous marriage on the DDAs has not been extensively studied. To the authors’ knowledge, this is the first study to address the relationship between consanguineous marriage and DDAs, both clinically and radiologically.…”

Genetic bases related to the development of non-syndromic dental agenesis: a literature review

“…Tallón-Walton, et al, (2010) found in Spain a prevalence of agenesis of 9.48% (7.25% excluding third molars) and 0.39% for oligodontia. Alsoleihat & Khraisat, (2014) found a prevalence of 11.8% (11.1% for men, 12.5% for women) in a study in the Druze population (Middle East). 90% of the individuals exhibited mild hypodontia (one or two missing teeth) and the most commonly absent teeth were the upper lateral incisors and the canines, followed by the lower and upper second premolars.…”