Hypoglycemic Effects of Unripe Pawpaw on Streptozotocin Induced Diabetic Albino Rats

Osadolor, HB; Ariyo, I.I.; Emokpae, Mathias Abiodun

doi:10.3923/rjmp.2011.90.94

Cited by 6 publications

(2 citation statements)

References 3 publications

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“…However, these agents are costly and exert some severe side effects. Efforts for the identification of effective antihyperglycemic agents have been concentrated on natural food products used in folk medicine [6][7][8]. Numerous traditional medicinal herb extracts have been employed for the treatment of DM due to its negligible side effects and cost-effectiveness [9].…”

Section: Introductionmentioning

confidence: 99%

The evaluation of the hypoglycemic effect of soft drink leaf extract of Phyllanthus amarus (Euphorbiaceae) in rats

Adedapo

Ofuegbe

2013

Journal of Basic and Clinical Physiology and Pharmacology

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Section: Introductionmentioning

confidence: 99%

The evaluation of the hypoglycemic effect of soft drink leaf extract of Phyllanthus amarus (Euphorbiaceae) in rats

Adedapo

Ofuegbe

2013

Journal of Basic and Clinical Physiology and Pharmacology

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“…Focus on plant research has increased worldwide in recent time and a large body of evidence has been collected to show the immense capacities of medicinal plants used in various traditional systems. Many data on the phytopharmacology have showed medicinal plants capacities in certain area of pharmacology (Osadalor et al, 2011) and researchers are also beginning to appreciate the role of medicinal plants in health care delivery (Kolwole et al, 2011). Medicinal plants and herbs have been used for many centuries for the treatment or prevention of diseases and for the promotion of good health.…”

Section: Introductionmentioning

confidence: 99%

Phytopharmacological Assessment from Two Medicinal Plants Used for Analgesic and Anti-inflammatory Purposes in Burkina Faso

Ouédraogo¹,

Konaté²,

Zerbo³

et al. 2013

RJASET

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The purpose of this investigation was to elucidate the anti-nociceptive and anti-inflammatory properties of aqueous acetone extracts from Cienfuegosia digitata Cav; and Sida Alba L. in Swiss mice, with an aim to provide a scientific basis for the traditional use of these plants in the treatment of inflammation disorders. In antiinflammatory activity, the carrageenan-induced paw edema and oil croton-induced ear edema in Swiss mice. As for analgesic effects, acetic acid writhing and formalin test methods were used in mice. About anti-inflammatory potential, the extracts at doses of 100; 200 and 400 mg/kg body weight produced significant comparatively to the control groups (p<0.05; p<0.01 and p<0.001) and we noticed a dose-dependent anti-inflammatory activity. The dose-dependent inhibition of edema was observed at 1; 2 and 3 h. However, extracts showed dose-dependent inhibition of croton oil induced ear oedema, at doses of 200; 300 and 500 µg/ear. As for analgesic activity, extracts produced significant analgesic effects in acetic acid writhing and formalin test method (p<0.05; p<0.01 and p<0.001) compared to the control groups and a dose-dependent inhibition was observed. The present study concludes that Cienfuegosia digitata Cav. and Sida Alba L. have anti-inflammatory and analgesic properties.

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African Medicinal Plants with Antidiabetic Potentials: A Review

2014

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Diabetes mellitus is one of the major health problems in Africa. The conventional oral synthetic antidiabetic drugs available to manage the disease are costly and not readily affordable to the majority of the affected population. Interestingly, the continent is endowed with a tremendous number of medicinal plants that have been explored for their folkloric treatment of diabetes mellitus. Scientific investigations have validated the antidiabetic potentials of a number of these medicinal plants but there is no repository with information on these scientifically investigated plants as a guide for future research. In this review article, all of the in vivo antidiabetic studies conducted between January 2000 and July 2013 on African plants are systematically compiled with a closer look at some relevant plants from the continent?s subregions. Plants of the Asteraceae and Lamiaceae families are the most investigated, and West Africa has the highest number of investigated plants. Although promising results were reported in many cases, unfortunately, only a few studies reported the partial characterization of bioactive principles and/or mechanisms of action. It is hoped that government agencies, pharmaceutical industries, and the scientific community will have a look at some of these plants for future research and, if possible, subsequent commercialization.

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Hypoglycemic Effects of Unripe Pawpaw on Streptozotocin Induced Diabetic Albino Rats

Cited by 6 publications

References 3 publications

The evaluation of the hypoglycemic effect of soft drink leaf extract of Phyllanthus amarus (Euphorbiaceae) in rats

The evaluation of the hypoglycemic effect of soft drink leaf extract of Phyllanthus amarus (Euphorbiaceae) in rats

Phytopharmacological Assessment from Two Medicinal Plants Used for Analgesic and Anti-inflammatory Purposes in Burkina Faso

African Medicinal Plants with Antidiabetic Potentials: A Review

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