<i>Dioscorea</i>(YAMS) - The Food of the Slaves, with Potentials for Newer Drugs: A review

Karnick, C. R.

doi:10.3109/13880206909066280

Cited by 13 publications

(8 citation statements)

References 43 publications

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“…In the course of the 16th century, French sailors erroneously changed the name from Inhame to Igname. Within this period, English seamen called the crop “yam.” Yam was a source of food for enslaved people during their East to West historic migration [ 2 ]. The roots, tubers and rhizomes of yams have been used since pre-historic times by aboriginal peoples as a food, as well as for traditional medicine [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials

Obidiegwu

Lyons

Chilaka

2020

Foods

142

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The quest for a food secure and safe world has led to continuous effort toward improvements of global food and health systems. While the developed countries seem to have these systems stabilized, some parts of the world still face enormous challenges. Yam (Dioscorea species) is an orphan crop, widely distributed globally; and has contributed enormously to food security especially in sub-Saharan Africa because of its role in providing nutritional benefits and income. Additionally, yam has non-nutritional components called bioactive compounds, which offer numerous health benefits ranging from prevention to treatment of degenerative diseases. Pharmaceutical application of diosgenin and dioscorin, among other compounds isolated from yam, has shown more prospects recently. Despite the benefits embedded in yam, reports on the nutritional and therapeutic potentials of yam have been fragmented and the diversity within the genus has led to much confusion. An overview of the nutritional and health importance of yam will harness the crop to meet its potential towards combating hunger and malnutrition, while improving global health. This review makes a conscious attempt to provide an overview regarding the nutritional, bioactive compositions and therapeutic potentials of yam diversity. Insights on how to increase its utilization for a greater impact are elucidated.

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Section: Introductionmentioning

confidence: 99%

The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials

Obidiegwu

Lyons

Chilaka

2020

Foods

142

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“…The tubers are roasted and cooked as vegetables and it can be taken as food by pigs. Bulbils are the best food for the diabetic patients (Karnick 1969) and root powder is the best medicine for tuberculosis. For the typhoid patients bulbils are the best precaution to prevent the disease (Abhyankar & Upadhyay 2011).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening and Antibacterial Activity of Dioscorea Bulbifera L. Fruits

Mohanty¹,

Choudhury²,

Kumar³

et al. 2021

PLANT ARCHIVES

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Dioscorea bulbifera (Pita aalu) is a medicinal plant belongs to famility Dioscoreaceae, used to cure various diseases like malaria, diarrhoea, diabetes, dysentery, cancer, piles and skin infections. We designed the present study to analyse phytochemical and antibacterial activity of D. bulbifera fruit so as to conform its edible property. For this we followed phytochemical screening of the fruit extracts and found that it is consist of tannin, saponin, phenols, steroids, terpenoids and some carbohydrates in high concentration. The antibacterial activity of aqueous extract of the fruit against Streptococcus mutans pathogen was determined by using agar well diffusion, disc diffusion and broth dilution assay. From the results it was confirmed that the aqueous extract of the fruits of D. bulbifera showed high inhibition zone at 100µg/ml is 19 mm in agar well diffusion, 14 mm in disc diffusion assay. The minimum inhibitory concentratiom (MIC) of extract of D. bulbifera arranged in respect to the parts from 100 µg/ml, 200 µg/ml, 300 µg/ml, 400 µg/ml, 500µg/ml and inoculums control showed visible growth due to no antimicrobial agents, whereas the broth control showed no growth due to absence of bacteria. Presence of primary and secondary metabolites indicates the nutraceutical value of D. bulbifera fruits. So the fruits of D. bulbifera can be used as a tool against antimicrobial resistance (AMR).

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“…The yam ( Dioscorea spp.) is widely cultivated in Africa, Asia and Central and South America and is a rich source of starch [ 11 , 15 ]. In East Asia, dried rhizomes of yam have been used as a traditional folk medicine for asthma, rheumatoid arthritis and bronchitis [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Atopic Properties of Gracillin Isolated from Dioscorea quinqueloba on 2,4-Dinitrochlorobenzene-Induced Skin Lesions in Mice

Jegal

Park

et al. 2018

Nutrients

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Naturally occurring saponins have been reported to have anti-inflammatory and immunomodulatory effects. However, the effects of gracillin, a main saponin component of Dioscorea quinqueloba (D. quinqueloba), on atopic dermatitis (AD), have not been previously studied. The aim of this study was to determine whether gracillin isolated from D. quinqueloba has an anti-AD effect on 2,4-dinitrochlorobenzene (DNCB)-induced AD-like skin lesions in SKH-1 hairless mice. Topical co-treatment of gracillin and DNCB for two weeks markedly reduced symptoms typical of AD (redness, itching, swelling and skin lichenification), decreased transepidermal water loss (TEWL) and increased skin hydration. In addition, gracillin strongly inhibited PI-induced IL-4 expression in RBL-2H3 cells and in the skins of AD mice. Our results suggest gracillin is a potential candidate for the prevention and treatment of AD and other inflammatory skin disorders.

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Dioscorea(YAMS) - The Food of the Slaves, with Potentials for Newer Drugs: A review

Cited by 13 publications

References 43 publications

The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials

The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials

Phytochemical Screening and Antibacterial Activity of Dioscorea Bulbifera L. Fruits

Anti-Atopic Properties of Gracillin Isolated from Dioscorea quinqueloba on 2,4-Dinitrochlorobenzene-Induced Skin Lesions in Mice

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