Metals are thought to have profound effects on the internal structures of molecular clouds in which stars are born. The absence of metals is expected to prevent gas from efficient cooling and fragmentation in theory. However, this effect has not yet been observed at low metallicity environments, such as in the early Universe and local dwarf galaxies, because of the lack of high spatial resolution maps of gas. We carried out ALMA observations of the carbon monoxide (CO) J=2-1 emission line at 1.4-parsec resolutions of a molecular cloud in DDO 70 at 7% solar metallicity, the most metal-poor galaxy currently known with a CO detection. In total, five clumps have been identified and they are found to follow more or less the Larson's law. Since the CO emission exists in regions with visual extinction A V around 1.0, we converted this A V to the gas mass surface density using a gas-to-dust ratio of 4,594±2,848 for DDO 70. We found that the CO clumps in DDO 70 exhibit significantly larger (on average four times) sizes than those at the same gas mass surface densities in massive star-formation regions of the Milky Way. The existence of such large clumps appears to be consistent with theoretical expectations that gas fragmentation in low metallicity clouds is suppressed. While our observation is only for one cloud in the galaxy, if it is representative, the above result implies suppressed gas fragmentation during the cloud collapse and star formation in the early Universe.