<i>T</i>
            <sub>2</sub>
            : The Transverse Relaxation Time

Boulby, Philip A.; Rugg‐Gunn, Fergus

doi:10.1002/0470869526.ch6

Cited by 29 publications

(30 citation statements)

References 246 publications

(365 reference statements)

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“…The 8-element array coil used to receive the signal intensity is rather less homogeneous, but receiver coil inhomogeneities will only be reflected in the S0 map (which is unused) and not in the T2 map. 16 The sequences used a variety of TEs and echo trains, each of which will have its own potential for stimulated echoes. The purpose of this article was not to study all of these effects in detail but to find a sequence that provided reproducible estimates of T2.…”

Section: Discussionmentioning

confidence: 99%

T2 Relaxometry of the Hippocampus at 3T

Bartlett¹,

Symms²,

Free³

et al. 2007

American Journal of Neuroradiology

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BACKGROUND AND PURPOSE: T2 mapping is useful for identifying and quantifying abnormalities of the hippocampus and amygdala. It is particularly useful in the presurgical evaluation of patients with temporal lobe epilepsy and for the identification of bilateral hippocampal sclerosis (HS). The purpose of this study was to implement and validate a dual-echo method for producing coronal T2 maps with complete coverage of the hippocampus and the rest of the brain on a 3T MR imaging scanner.

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Section: Discussionmentioning

confidence: 99%

T2 Relaxometry of the Hippocampus at 3T

Bartlett¹,

Symms²,

Free³

et al. 2007

American Journal of Neuroradiology

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“…Several factors other than the interstitial fluid in TA may contribute to the variation in 2 of TA and soleus. Generally 2 values correlate most strongly with bulk water content of the tissue [47]. Tissues with high concentrations of aliphatic lipid protons have longer 2 .…”

Section: Discussionmentioning

confidence: 96%

Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

et al. 2013

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properly cited.Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS) acquired extracellular fluid (ECF), intracellular fluid (ICF), total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI) acquired transverse relaxation times ( 2 ), and apparent diffusion coefficient (ADC) of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were collected in 32 healthy individuals on two occasions and analyzed by a single rater. On both occasions, MRI measures were collected from tibialis anterior (TA), medial (MG), and lateral gastrocnemius (LG) and soleus muscles following the cBIS data acquired using XiTRON Hydra 4200 BIS device. The intraclass correlation coefficients (ICC 2,1 ), coefficient of variation (CV), and agreement between MRI and cBIS data were also calculated. Results. ICC 2,1 values for cBIS, 2 , and ADC ranged from 0.56 to 0.92, 0.96 to 0.99, and 0.05 to 0.56, respectively. Relative variability between measures (CV) ranged from 14.6 to 25.6% for the cBIS data and 4.2 to 10.0% for the MRIacquired data. The ratio of ECF : ICF could significantly predict 2 of TA and soleus muscles. Conclusion. MRI-acquired measures of 2 had the highest test-retest reliability of muscle hydration with the least error and variation on repeated testing. Hence, 2 of a muscle is the most reliable and stable outcome measure for evaluating individual muscle hydration.

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“…The T2 relaxation time reflects the time it takes the dipoles to disperse energy following excitation. 109 The T2 relaxation time of cartilage is a complex measurement that is influenced by multiple factors, including water and macromolecular concentration, [110][111][112][113] organization of the collagen fiber network, [114][115][116] cartilage loading, 117-119 and orientation of cartilage relative to the main magnetic field. 120 Thus, changes in the T2 relaxation time of cartilage may be difficult to interpret because of the multiple competing biological and mechanical factors that influence the measurement.…”

Section: T2 Mappingmentioning

confidence: 99%