Thermonuclear ignition condition for deuterium-tritium plasmas can be achieved in compact, high magnetic field devices such as Ignitor. The main scientific goals, the underlying physics basis, and the most relevant engineering solutions of this experiment are described. Burning plasma conditions can be reached either with ohmic heating only or with small amount of auxiliary power in the form of ICRH waves, and this condition can be sustained for a time considerably longer than all the relevant plasma time scales. In the reference operating scenario, no transport barriers are present, and the resulting thermal loads on the plasma facing component are estimated to be rather modest, thanks to the high edge density and low edge temperature that ensure an effective intrinsic radiating mantle in elongated limiter configurations. Enhanced confinement regimes can also be obtained in configurations with double X-points near the first wall.