Identification of crinosterol from astigamatid mites

Murakami, Kenjiro; Watanabe, Bunta; Nishida, Ritsuo; Mori, Naoki; Kuwahara, Yasumasa

doi:10.1016/j.ibmb.2007.02.007

Cited by 6 publications

(1 citation statement)

References 30 publications

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“…Regarding the first sterol, there is specific scientific evidence of its biological activity, but it is known that many sterols are present in medicinal fungi, and some of them are used in traditional medicine due to their anti-aging properties, for their usefulness in treating neurodegenerative diseases such as Alzheimer's [24] and for their anti-inflammatory and photoprotective activities [25] and their antitumor, cytotoxic and immunosuppressive activities [26,27]. The second sterol is commonly known as crinosterol, and it is present in seaweed and marine invertebrates [28][29][30][31]. It has been used in the treatment of Alzheimer's due to its anti-aging properties and neuroprotective functions [32].…”

Section: Phytochemical Studymentioning

confidence: 99%

Usnea aurantiaco-atra (Jacq) Bory: Metabolites and Biological Activities

Vega-Bello,

Moreno,

Estellés-Leal

et al. 2023

Molecules

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Background: Lichens are complex symbiotic associations between a fungus and an alga or cyanobacterium. Due to their great adaptability to the environment, they have managed to colonize many terrestrial habitats, presenting a worldwide distribution from the poles to the tropical regions and from the plains to the highest mountains. In the flora of the Antarctic region, lichens stand out due to their variety and development and are a potential source of new bioactive compounds. Methods: A phytochemical study of the Antarctic lichen Usnea aurantiaco-atra (Jacq) Bory was conducted with the intention of determining the most important metabolites. In addition, the cytotoxic and antioxidant activities of its extracts were determined. Results: Cytotoxicity studies revealed that the hexane extract contains usnic acid as a majority metabolite, in addition to linoleic acid, ergosterols and terpenes, and demonstrates cytotoxic activity against an A375 melanoma cell line. On the other hand, the presence of total phenols in the extracts did not influence their antioxidant activity. Conclusions: U. aurantiaco-atra contains mainly usnic acid, although there are terpenes and ergosta compounds that could be responsible for its cytotoxic activity. The presence of phenols did not confer antioxidant properties.

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Section: Phytochemical Studymentioning

confidence: 99%

Usnea aurantiaco-atra (Jacq) Bory: Metabolites and Biological Activities

Vega-Bello,

Moreno,

Estellés-Leal

et al. 2023

Molecules

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Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae)

Aboshi

Shimizu

Nakajima

et al. 2013

Insect Biochemistry and Molecular Biology

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A concise synthesis of β-sitosterol and other phytosterols

Hang

Dussault

2010

Steroids

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A convenient synthesis of sidechain-modified phytosterols is achieved via a temporary masking of the stigmasterol 5,6-alkene as an epoxide. Following performance of the desired modification, the alkene is regenerated through a mild deoxygenation. The approach is applied to the syntheses of β-sitosterol and campesterol acetate, and suggests a facile route to the (Z)-isomers of Δ 22-23 phytosterols.

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Identification of crinosterol from astigamatid mites

Cited by 6 publications

References 30 publications

Usnea aurantiaco-atra (Jacq) Bory: Metabolites and Biological Activities

Usnea aurantiaco-atra (Jacq) Bory: Metabolites and Biological Activities

Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae)

A concise synthesis of β-sitosterol and other phytosterols

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