Il-4: Prediktor Anti Inflamasi Pada Stroke Iskemik ?

Abstract

<p>The brain ischemia due to vascular occlusion, especially in the main cerebral artery, could trigger the microglia as a natural immune cell in the brain. These activated microglia will turn up the inflammation cascade in the ischemic area. Interleukin-4 (IL-4) has a vital role in the microglial alteration to become an anti-inflammatory phenotype, which wind up the expression of MHC II and CD11c. Moreover, previous studies has supported that the stimulation of IL-4 in the culture of microglia/macrophage will produce this kind of “alternative” phenotype or neuroprotective phenotype, through the fall of TNF and rise of IGF-1. However, only a few have discussed the role and profile of IL-4 in ischemic stroke. This review article will cover the possibility of IL-4 role as an anti-inflammatory predictor in ischemic stroke.</p><p><strong>Keywords: Interleukin-4, microglia, ischemic stroke, inflammation</strong></p>

The Effect Of Passive Range Of Motion (ROM) on Increasing Elbow Joint Angles of Stroke Patients

“…The results of the study showed that the majority of respondents' length of stay in this study was 1-5 days, as many as 19 people (63.3%). The results of this study are in line with the results of research conducted by [7] which states that the length of stroke patient care is in a total of days. Respondents who had a stroke were treated for at least 4 days and the longest being treated at 15 days.…”