Ileal carcinoid tumor as a cause of massive lower-GI bleeding: the role of capsule endoscopy

Forner, Alejandro; Mata, Alfredo; Puig, María Margarida Bassols i; Varela, Marı́a; Rodríguez, Francisco Gea; Llach, Josep; Feu, Faust; Bordas, Josep M.; Piqué, Josep M.

doi:10.1016/s0016-5107(04)01814-0

Cited by 14 publications

(9 citation statements)

References 15 publications

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“…Obscure GI bleeding is known to occupy about 5% of all GI bleedings, and 75% of these are thought to be a bleeding from a lesion of the small bowel 13. For the evaluation of the small bowel, capsule endoscopy, push enteroscopy, double balloon enteroscopy, angiography, and barium small bowel examination are available 13,14. A retrospective study reported that 3 cases of ectopic pancreas causing bleeding in the small bowel among 76 cases of obscure GI bleeding were identified using angiography, barium small bowel examination, and enteroscopy 7.…”

Section: Discussionmentioning

confidence: 99%

Ectopic Pancreas Bleeding in the Jejunum Revealed by Capsule Endoscopy

et al. 2012

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Ectopic pancreas is defined as pancreatic tissue found outside the usual anatomic location. It is often found incidentally at different sites in the gastrointestinal (GI) tract. The incidence of ectopic pancreatic tissue in autopsy series is 1% to 2%, with 70% of the ectopic lesions found in the stomach, duodenum and jejunum. Although it is usually a silent anomaly, an ectopic pancreas may become clinically evident when complicated by inflammation, bleeding, obstruction or malignant transformation. We report a case of ectopic pancreas located in the jejunum and presenting as an obscure GI bleeding, which was diagnosed by capsule endoscopy.

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Section: Discussionmentioning

confidence: 99%

Ectopic Pancreas Bleeding in the Jejunum Revealed by Capsule Endoscopy

et al. 2012

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“…Upper endoscopy and colonoscopy are both operator-dependent procedures that are limited by anatomic boundaries. Case reports suggest that capsule endoscopy has a role in the detection of small bowel lesions, which are poorly visualized by esophagogastroduodenoscopy (EGD) [ 13 , 14 ]. No modality has been established as the “gold standard” diagnostic study for small bowel tumors.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Gastrointestinal Carcinoid Tumor with Unknown Primary Site

Liang

Shaffer

2007

Radiology Case Reports

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Carcinoid tumors are rare and slow growing malignancies derived from enterochromaffin cells. Two-thirds of carcinoid tumors arise in the gastrointestinal tract, and in 3% of these cases the primary site cannot be determined. Presenting symptoms depend on the location of the primary tumor but may be nonspecific, and in 13% of patients distant metastases are discovered on diagnosis. The classic carcinoid syndrome occurs in less than 10% of cases and only after metastasis to the liver. We present a case of a young woman with a gastrointestinal carcinoid tumor of unknown site that had metastasized to the liver. We also provide a review of the current diagnostic modalities. Familiarity with the signs and symptoms of carcinoid tumors and the diagnostic techniques thereof may facilitate early detection and improved outcome.

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“…Videocapsule endoscopy (Video)capsule endoscopy has obvious potential for surveillance of the small intestine for carcinoid tumors (28,29).…”

Section: Endoscopic Ultrasoundmentioning

confidence: 99%

Carcinoid syndrome: diagnosis and medical management

Lely¹,

Herder²

2005

Arq Bras Endocrinol Metab

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Gastro-intestinal carcinoids are slow growing tumors arising from enterochromaffin or Kulchitsky cells. Their clinical presentation depends on what combination of bioactive substances is secreted. Midgut carcinoid can present with the carcinoid syndrome in the presence of liver metastases. Its most typical clinical manifestations include cutaneous flushing and diarrhea. A nonspecific biochemical tumor marker for carcinoid tumors is serum chromogranin A and a specific marker for the carcinoid syndrome is the increased urinary excretion of 5-hydroxy indole acetic acid (5-HIAA). Localizing studies in carcinoid tumors/syndrome are: transabdominal ultrasonography (US), endoscopy, endoscopic US, videocapsule endoscopy, computerized tomography, magnetic resonance imaging, selective abdominal angiography, 111 In-pentetreotide scintigraphy (and intraoperative radionuclide probe), 1 2 3 I ( 1 3 1 I ) -metaiodobenzylguanidine (MIBG) scintigraphy, bone scintigraphy and 11 C-5-HT positron emission tomography (PET). Therapies for carcinoid tumors/syndrome are: surgery, somatostatin analogs, interferon-alpha, radiotherapy, liver dearterialization, liver (chemo, or radio)-embolization, alcohol sclerotherapy of liver metastases, radiofrequency ablation of liver metastases, cryosurgery of liver metastases, occasionally liver transplantation, radiotherapy-coupled somatostatin analogs, 131 I-MIBG and occasionally chemotherapy. Carcinóides gastro-intestinais são tumores de crescimento lento originários das células enterocromafínicas ou de Kulchitsky. Sua apresentação clínica depende das combinações de substâncias bioativas que são secretadas. Carcinóides de intestino delgado podem se apresentar com síndrome carcinóide na presença de metástases hepáticas. A manifestação clínica típica inclui flushing cutâneo e diarréia. A cromogranina-A é um marcador bioquímico tumoral inespecífico de tumores carcinóides e o aumento da excreção urinária de ácido 5-hidroxiindolacético (5-HIAA), um marcador específico para a síndrome carcinóide. Estudos de localização nos tumores/síndrome carcinóide são: ultrassonografia (US) abdominal, endoscopia, US endoscópica, endoscopia com vídeo-cápsula, tomografia computadorizada, ressonância magnética, angiografia abdominal seletiva, cintilografia com 111 In-pentetreotide (e sonda radioisotópica intraoperatória), cintilografia com 123 I ( 131 I) -metaiodobenzilguanidina (MIBG), cintilografia óssea e tomografia por emissão de pósitron ( 11 C-5-HT). Tratamento para tumores/síndrome carcinóide são: cirurgia, análogos de somatostatina, interferon-alfa, radioterapia, embolização arterial hepática, quimioembolização hepática, escleroterapia alcoólica de metástases hepáticas (MH), ablação por radiofreqüência de MH, criocirurgia de

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Ileal carcinoid tumor as a cause of massive lower-GI bleeding: the role of capsule endoscopy

Cited by 14 publications

References 15 publications

Ectopic Pancreas Bleeding in the Jejunum Revealed by Capsule Endoscopy

Ectopic Pancreas Bleeding in the Jejunum Revealed by Capsule Endoscopy

Metastatic Gastrointestinal Carcinoid Tumor with Unknown Primary Site

Carcinoid syndrome: diagnosis and medical management

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