Immune responses to exercise in children treated for cancer.

Shore, Susan; Rj, Shepard

doi:10.1097/01893697-200119020-00035

Cited by 33 publications

(100 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Inclusion criteria were the following: (1) studies limited to humans of any ethnic origin, (2) written in English, (3) full text (versus abstract only) available and (4) X50% of cancer patients/survivors used as study participants having hematological cancer diagnosis. One study 48 that stated participants were 'predominantly lymphoblastic leukemia' was assumed to imply at least half of survivors were hematological cancer and was included. Provided they met the criteria of 50% or more of the total survivor population having hematological cancer, we also included intervention exercise studies on HSCT patients regardless of their primary tumor site because many hematological cancer survivors undergo HSCT.…”

Section: Methodsmentioning

confidence: 99%

“…A small intervention study that included supervised and home-based exercise increased physical activity. 72 Shore and Shepard 48 reported that a 12-week aerobic intervention of 30 min of aerobic exercise that was partially supervised (that is, by a fitness professional once per week and by parents twice per week) significantly improved fitness in three pediatric ALL survivors (13-14 years) within 4 weeks of the conclusion of induction therapy. A recent community-based intervention showed improvements in physical activity levels and physical fitness in adolescents surviving cancer, though they returned to low physical activity levels shortly after they finished the program.…”

Section: Adultsmentioning

confidence: 99%

“…However, a 20-week aerobic intervention of thrice weekly activity for 30-40 min after treatment reduced fatigue in Hodgkin lymphoma survivors. 70 Finally, Shore and Shepard 48 reported that a 12-week aerobic intervention of 30 min of Outcomes examined in at least two studies.…”

Section: Adultsmentioning

confidence: 99%

“…Twelve studies, [42][43][44][45][46][47][48][68][69][70][71][72] including two RCT 42,44 and seven high-quality studies [42][43][44][45][46]69,71 evaluated the effects of physical activity interventions on outcomes in children with pediatric cancer who did not undergo HSCT. One study of high quality 68 evaluated the effects of a single (30 min) exercise bout.…”

Section: Adultsmentioning

confidence: 99%

See 3 more Smart Citations

Exercise in adult and pediatric hematological cancer survivors: an intervention review

et al. 2010

View full text Add to dashboard Cite

Observational research has shown that the physical activity levels of survivors of hematological cancer are low, with deleterious health consequences. This review summarizes the research on exercise interventions in adult and pediatric hematological cancer survivors. We searched MEDLINE, SPORTDiscus, CINAHL, Embase, Cochrane and PEDro through September 2009 for exercise intervention studies in children and adults with any type of hematological cancer. In the 24 adult intervention studies reviewed, we found strong evidence (that is, X3 high-quality studies and X75% reporting a significant benefit) for a benefit on body composition. Weak, but promising, evidence (X3 high-quality studies, but o75% reporting a significant benefit) was found for cardiorespiratory fitness, fatigue, muscle strength, physical functioning and quality of life. In pediatric interventions (13 studies), we found strong evidence for a benefit on muscle strength and cardiorespiratory fitness, particularly, if training was conducted in the hospital setting. Evidence is weak for ankle dorsiflexion, physical functioning and body composition. No exerciserelated risks were identified in adults or children studies. Though more randomized controlled trials are needed, a growing body of literature supports the notion that regular physical activity is safe and has potential benefits for both adult and pediatric hematological cancer survivors.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Adultsmentioning

confidence: 99%

Section: Adultsmentioning

confidence: 99%

Section: Adultsmentioning

confidence: 99%

See 2 more Smart Citations

Exercise in adult and pediatric hematological cancer survivors: an intervention review

et al. 2010

View full text Add to dashboard Cite

show abstract

“…10 Marchese et al 21 recently showed that a 4-month home exercise program consisting of ankle dorsiflexion stretching, lower extremity strengthening, and aerobic exercise in children (age 4-10 years) with ALL receiving maintenance chemotherapy improved their muscle function, stamina, and QOL. A preliminary report by Shore and Shephard 22 indicated similar outcomes after a 12-week extrahospital aerobic exercise program in children (mean age 14 years) receiving chemotherapy against various types of cancer. Importantly, there are no reported detrimental effects of exercise training in cancer patients of any age to date.…”

mentioning

confidence: 80%

Intrahospital supervised exercise training: a complementary tool in the therapeutic armamentarium against childhood leukemia

et al. 2005

View full text Add to dashboard Cite

Physical exercise and immune system function in cancer survivors

Fairey

Courneya

Field

et al. 2002

Cancer

141

View full text Add to dashboard Cite

BACKGROUNDThere are a limited number of interventions for cancer survivors following completion of primary therapy that might reduce the risk of cancer recurrence and/or secondary malignancies and increase survival times. It has been proposed that physical exercise may be beneficial by enhancing the anticancer immune system response. The purpose of the current article is to: 1) briefly describe the immune system response to tumors, 2) discuss the impact of anticancer therapy on immune system function in cancer survivors, 3) provide a systematic and comprehensive review of the extant literature examining physical exercise and immune system function in cancer survivors, and 4) offer a critical analysis of this literature and outline directions for future research.METHODSA comprehensive literature search up to March 2001 identified empirical articles that examined the effects of physical exercise training on immune system function in cancer survivors from CD‐ROM database searches and manual searches.RESULTSTo the authors' knowledge, six empirical studies published between 1994 and 2000 have examined physical exercise and immune system function in cancer survivors. Overall, four out of six studies reported statistically significant improvements in a number of cancer‐related immune system components as a result of exercise. However, there are several limitations that must be considered when interpreting the findings of these studies. These limitations involve the samples, designs, physical exercise interventions, physical fitness assessments, and immunologic assessments.CONCLUSIONSAdditional research is needed to determine if physical exercise in cancer survivors may reduce the risk of cancer recurrence and secondary malignancies and increase survival times. Cancer 2002;94:539–51. © 2002 American Cancer Society.

show abstract

Immune responses to exercise in children treated for cancer.

Cited by 33 publications

References 0 publications

Exercise in adult and pediatric hematological cancer survivors: an intervention review

Exercise in adult and pediatric hematological cancer survivors: an intervention review

Intrahospital supervised exercise training: a complementary tool in the therapeutic armamentarium against childhood leukemia

Physical exercise and immune system function in cancer survivors

Contact Info

Product

Resources

About