2006
DOI: 10.1016/j.bone.2005.10.021
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Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation

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Cited by 48 publications
(32 citation statements)
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“…It has been demonstrated previously that in the course of neuronal induction, human MSCs develop cellular features of neuritogenesis and synaptogenesis similar to those observed in immature neurons (25). In this study, the addition of 40 mM DHA and 40 mM AA to the induction differentiation medium enhanced the neurite growth of neuron-like cells.…”
Section: Discussionsupporting
confidence: 75%
“…It has been demonstrated previously that in the course of neuronal induction, human MSCs develop cellular features of neuritogenesis and synaptogenesis similar to those observed in immature neurons (25). In this study, the addition of 40 mM DHA and 40 mM AA to the induction differentiation medium enhanced the neurite growth of neuron-like cells.…”
Section: Discussionsupporting
confidence: 75%
“…Besides, similar immature action potentials and current-voltage relationships are often observed for developing human neurons [26] and neuron-like cells differentiated from stem cells isolated from humans [14,25,28,30,37,47,48] or from rodents [29,32,33,49,50]. Finally, consistent with those previously published studies [9,[11][12][13][14]25,47,48,[51][52][53][54], we confirmed that neuron-like cells with neuronal morphology usually express neuronal and not glial markers (Fig. 1A).…”
Section: Membrane Properties Of Neuron-like Cells Differentiated Fromsupporting
confidence: 91%
“…It is well known that one of the main characteristics of MSCs is their differentiation into the cell lineages of mesodermal origin [9], while the differentiation into the cell lineages of endo-or ectodermal origin is still a matter of debate and criticism [46][47][48]. Regardless of these concerns, the MSCs can express some pluripotency-related genes (markers).…”
Section: Discussionmentioning
confidence: 99%