Immunoglobulin changes in a pediatric otolaryngic patient sample subsequent to T &amp; A

Veltri, Robert W.; Sprinkle, Philip M.; Keller, Sue; Chicklo, James M.

doi:10.1017/s0022215100076064

Cited by 34 publications

(9 citation statements)

References 23 publications

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“…Levels of antibody before and after tonsillectomy have been studied; Ogra (1971) thought that polio type I fell significantly, and Veltri et al (1972) showed a fall in IgG levels (though no change in secretory IgA) and antibodies to some viral infections. There is some doubt about the effect of tonsillectomy on cell-mediated immunity and the later development of, for example, Hodgkin's disease (Vianna et at.…”

Section: Discussionmentioning

confidence: 99%

Tonsils and Adenoids: What do we Find?

Wright

1978

J R Soc Med

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In the last twelve months, 216 pairs of paiatine tonsils were removed in the Ear, Nose and Throat Department of Manchester Royal Infirmary. These operations were usually in children, from whom adenoid tissue (the pharyngeal tonsil) was removed at the same time. In the absence of a special reason, neither tonsils nor adenoids from children find their way to the surgical histology department: this is true enough to require special requests for specimens so that other people can see these organs. Adult tonsils are, of course, different in this respect.The age and sex distribution of tonsillectomy for the last four years is shown in Table I, and is remarkable for the high figure for males in the first two five-year periods and for females in the 10-25 year age group. The figures for the four-year totals of females are highly significant, and in fact the female preponderance in the adolescent and young adult groups brings-the total figures up to a near-equal distribution for the sexes, in spite of the early male preponderance. Very few tonsils are removed in Manchester Royal Infirmary before the age of 4, and hence the male period of risk appears to be 3-9 years of age and that of females 10-25 years.

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Section: Discussionmentioning

confidence: 99%

Tonsils and Adenoids: What do we Find?

Wright

1978

J R Soc Med

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“…A decrease in the immunological factors' values postoperatively did not always mean a drop in immunity. Veltri et al [4], for instance, did not use a control group and noticed a significant decrease in IgG levels postoperatively, but that decrease was to normal Page 10 of 29 A c c e p t e d M a n u s c r i p t 10 levels, meaning that the preoperative levels were abnormally elevated. On the other hand, Donovan and Soothill [5] noticed abnormally preoperative low levels of serum IgA in their patients, which persisted postoperatively.…”

Section: Discussionmentioning

confidence: 99%

The effect of tonsillectomy on the immune system: A systematic review and meta-analysis

Bitar

Dowli

Mourad

2015

International Journal of Pediatric Otorhinolaryngology

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“…In chronic cases removal may not have an appreciable effect. In these cases an immune complex type disease may already have developed and bacteria in the entire oropharynx may be Immune complexes in the middle eavjluid 543 responsible for chronic middle ear mucosal irritation (Veltri et al, 1972).…”

Section: Discussionmentioning

confidence: 99%

Immune Complexes in the Middle Ear Fluid and Adenoid Tissue in Chronic Secretory Otitis Media

Palva

Lehtinen

Virtanen

1983

Acta Oto-Laryngologica

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Specimens of middle ear effusion and adenoid tissue were studied for bacteria and pneumococcal capsular antigen in 107 patients with secretory otitis media. 120 of 163 middle ear effusion samples (73.6%) were negative on bacterial culture. Hemophilus influenzae was present in 9.2% and Streptococcus pneumoniae in 1.8%. Hemophilus influenzae was cultured from 44.8% and Streptococcus pneumoniae from 35.5% of 107 adenoid tissue specimens. Free pneumococcal capsular antigen was demonstrated in 10.4% of the middle ear fluids and this figure rose to 23% when antigen was liberated from the immune complexes by heating. The corresponding figures for adenoid tissue suspension were 27.1% and 39%. The adenoid tissue or the lymphoid tissue of the entire oropharynx could act as the source of antigen which could maintain immune complex disease in some patients suffering from secretory otitis media.

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Immunoglobulin changes in a pediatric otolaryngic patient sample subsequent to T & A

Cited by 34 publications

References 23 publications

Tonsils and Adenoids: What do we Find?

Tonsils and Adenoids: What do we Find?

The effect of tonsillectomy on the immune system: A systematic review and meta-analysis

Immune Complexes in the Middle Ear Fluid and Adenoid Tissue in Chronic Secretory Otitis Media

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