Impact of Co-Occurring Psychiatric Disorders on Retention in a Methadone Maintenance Program: An 18-Month Follow-Up Study

Abstract

We assess the influence of co-occurring psychiatric disorders on retention in 189 opioid dependent patients in a methadone maintenance treatment (MMT) and determine the incidence of psychiatric co-morbidity during an 18-month follow-up period. About 68.5 % were retained in the MMT. Neither co-occurring mental disorders (chi-square = 0.303, df = 1, p = 0.622) nor methadone doses [85 (88.9) vs. 79.2 (85) mg/day, p = 0.672] were related to retention. In the follow-up period 19 new diagnoses were made, mainly major depression and antisocial and borderline personality disorders. Co-occurring psychiatric disorders should be assessed during MMT follow-up.

Incidence of psychopathology in a cohort of young heroin and/or cocaine users

“…This is a repeated finding in followup studies both in the general population and in substance users, whether in treatment or out of treatment (Astals et al, 2009;Grant et al, 2008;Martin-Santos et al, 2009). Consistent with the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) study, being a woman was associated with a higher likelihood of developing a new non-SUD Axis I disorder; however, we did not find gender differences in the risk of incident SUD, whereas the NESARC study found a greater risk of incident drug dependence for men (Grant et al, 2008).…”

A comparative study of the effectiveness of group-based cognitive behavioral therapy and dialectical behavioral therapy in reducing depressive symptoms in Iranian women substance abusers

“…Basic depression, anxiety, borderline personality disorder, and antisocial personality disorder are the most common psychiatric diagnoses among addicts (Astals et al, 2009;Roberts, Roberts, & Xine, 2007). Beck's theory of depression (Beck, Rush, Shaw, & Emery, 1979) proposes that difficult early life experiences can make an individual vulnerable to depression through the development of unhelpful core beliefs about the self, others, and the world.…”

Psychiatric comorbidities in opioid-dependent patients undergoing a replacement therapy programme in Spain: The PROTEUS study

“…In a Spanish sample of OD patients in a methadone maintenance programme (Astals et al, 2009), 32.3% had co-occurring mental disorders or a dual diagnosis (over half of them with Axis I disorders alone), and the prevalence seems to be increasing with time (Sanvisens et al, 2014).…”