Impact of comorbidity on health-related quality of life in men undergoing radical prostatectomy: Data from CaPSURE

Arredondo, Shelley A.; Elkin, Eric P.; Marr, Paige L.; Latini, David; DuChane, Janeen; Litwin, Mark S.; Carroll, Peter R.

doi:10.1016/j.urology.2005.09.006

Cited by 47 publications

(30 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our data support previous work showing that greater number of comorbidities is associated with worse HRQOL both before and after RP. 4,6 In our study, all comorbidity groups experienced similar absolute declines from baseline HRQOL at 24 months in all domains. This suggests that all men will experience the same absolute long-term reductions in HRQOL after treatment, regardless of comorbidity status.…”

Section: Discussionsupporting

confidence: 62%

“…A previous study showed that men with no comorbidity had the highest baseline sexual function before RP, but by 24 months after treatment, differences between comorbidity groups were no longer apparent; the authors posited that this suggests different rates of recovery among comorbidity groups. 4 We observed that men with worse comorbidity had less initial decline from baseline but slower recovery of sexual function after RP. With longer follow-up, it is possible that the comparatively slow recovery among men with worse comorbidity may lead to increasing divergence from baseline sexual function.…”

Section: Comorbidity Severity Predicts Hrqol Tj Daskivich Et Almentioning

confidence: 59%

“…These results are similar to those observed when using comorbidity count as a comorbidity assessment tool. 4 A formal comparison of the TIBI-CaP and other methods of comorbidity assessment is underway.…”

Section: Comorbidity Severity Predicts Hrqol Tj Daskivich Et Almentioning

confidence: 99%

“…3 In addition to predicting survival, several studies have also observed a correlation between comorbidity and health-related quality of life (HRQOL). A raw estimate of overall comorbidity-comorbidity count-has been associated with worse baseline and post-prostatectomy HRQOL across general and diseasespecific domains, 4 and decreased likelihood of returning to baseline physical function. 5 Increasing severity of specific comorbidities, such as cardiovascular disease, has also been linked with worse baseline and posttreatment HRQOL scores.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer

Daskivich

Poll‐Franse

Kwan

et al. 2010

Prostate Cancer Prostatic Dis

View full text Add to dashboard Cite

Commonly used measures of comorbidity assess comorbidity number and type but not severity. We sought to evaluate the impact of comorbidity severity on longitudinal health-related quality of life (HRQOL) in men treated with radical prostatectomy (RP) or radiation therapy (RT) using the Total Illness Burden Index for prostate cancer (TIBI-CaP). We sampled 738 men with non-metastatic prostate cancer treated with RP or RT from the Cancer of the Prostate Strategic Urologic Research Endeavor registry. We examined the impact of comorbidity severity on generic and disease-specific HRQOL at baseline and at 6, 12, 18 and 24 months post-treatment. Men with worse TIBI-CaP comorbidity had significantly lower baseline and post-treatment HRQOL in all domains at all time points. In a multivariate model, men with moderate or severe TIBI-CaP comorbidity had significantly worse HRQOL scores at 12 and 24 months after treatment in all domains except sexual and urinary function (Po0.05); in these domains, severe comorbidity was predictive of lower HRQOL (Po0.05). Comorbidity groups had similar absolute declines in HRQOL from baseline to 6 and 24 months after treatment. Although comorbidity groups experienced similar long-term declines from baseline HRQOL after treatment, men with more severe comorbidity had significantly lower baseline scores and therefore poorer long-term HRQOL.

show abstract

Section: Discussionsupporting

confidence: 62%

Section: Comorbidity Severity Predicts Hrqol Tj Daskivich Et Almentioning

confidence: 59%

Section: Comorbidity Severity Predicts Hrqol Tj Daskivich Et Almentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer

Daskivich

Poll‐Franse

Kwan

et al. 2010

Prostate Cancer Prostatic Dis

View full text Add to dashboard Cite

show abstract

“…There have been number of studies examining the impact of cardiovascular diseases either single or co-morbid conditions on the HRQL, especially the co-morbidity of hypertension [9,10]. However, none of these studies aimed to elicit this problem in people with hypertension in the UAE.…”

Section: Introductionmentioning

confidence: 99%

Quality Of Life of Hypertensive Patients on Different Types of Antihypertensive Medications

Shanableh¹

2014

iosrphr

View full text Add to dashboard Cite

: More than three quarter of the total death in the UAE is due to cardiovascular diseases. Health Related Quality of Life (HRQL) is a broad multidimensional concept that usually includes 3% of hypertensive patients used a combination therapy of two medicines; 33% used Angiotensin receptor blockers (ARB) + Diuretics and 20% used the combination of B-blockers + Diuretics. Only 6% of the patients used B-Blockers class for their treatment. Data were analyzed by SPSS. The mean values of Physical Functioning (PF), Role-Physical (RP), Bodily Pain (BP), General Health (GH), Vitality (V), Social Functioning (SF), Role Emotional (RE), Mental Health (MH), Physical Components Summary (PCS), and Mental Components Summary (MCS) scores were 62.5, 62.9, 72.1, 62.1, 64.5, 76.7, 68.8, 66.2, 47.0, and 47.8

show abstract

Influence of co-morbidity on long-term quality of life after oesophagectomy for cancer

Djärv

Derogar

Lagergren

2014

British Journal of Surgery

View full text Add to dashboard Cite

show abstract

Impact of comorbidity on health-related quality of life in men undergoing radical prostatectomy: Data from CaPSURE

Cited by 47 publications

References 16 publications

From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer

From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer

Quality Of Life of Hypertensive Patients on Different Types of Antihypertensive Medications

Influence of co-morbidity on long-term quality of life after oesophagectomy for cancer

Contact Info

Product

Resources

About