Impact of extra-corporeal membrane oxygenation on outcome of aluminium phosphide poisoning complicated with myocardial dysfunction

“PGI Score”: A Simplified Three-point Prognostic Score for Acute Aluminum Phosphide Poisoning

“…The score can also be useful for immediately commencing the emerging novel interventions with improved survival (e.g., glucose–insulin–potassium infusion, extracorporeal membrane oxygenation) in high-risk patients from resource-limited countries. 12 , 21 …”

Performance of extracorporeal membrane oxygenation in patients with fatal paraquat poisoning: grasp for straws?

“…Previous studies have shown that ECMO has attracted more attention in severe poisoning, such as through irritant gases, PQ, and aluminum phosphide. [6][7][8] E CMO can preserve tissue perfusion by augmenting oxygenated venous blood via V-V ECMO, enhancing perfusion to critical organs, and improving oxygenation via V-A ECMO. L ung transplantation may be the most effective end-stage therapy, owing to irreversible pulmonary fi brosis induced by PQ, in which ECMO can be the transitional supportive therapy.…”

Successful Treatment of Severe Myocardial Injury Complicated With Refractory Cardiogenic Shock Caused by AOPP Using Extracorporeal Membrane Oxygenation

“…Vardon [15] et al reported the successful rescue of patients with intractable ventricular arrhythmia and cardiogenic shock caused by severe yew poisoning using VA-ECMO. In addition, ECMO was used in patients with severe aluminum phosphide poisoning, reducing the mortality rate from 84.4-40% [5] . In addition, in a retrospective cohort analysis of persistent cardiac arrest or severe shock caused by drug poisoning, Masson [16] et al found that the survival rate of patients who received ECMO was as high as 86%, while that of patients who did not receive ECMO was only 48%.…”

“…Among them, cardiotoxicity mainly manifests as myocardial congestion, interstitial edema, ischemia and reversible interstitial in ammation [3] . However, when AOPP causes severe myocardial injury with refractory cardiogenic shock, the mortality rate exceeds 60% [4,5] .…”