Impact of newly diagnosed breast cancer on quality of life among Chinese women

Lü, Wei; Cui, Yong; Zheng, Ying; Gu, Kai; Cai, Hui; Li, Qiong; Wang, Zheng

doi:10.1007/s10549-006-9318-5

Cited by 51 publications

(66 citation statements)

References 49 publications

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“…Thus far, the Pathways Study has achieved a participation rate similar to other breast cancer prognosis studies of more limited scope [22,36,37]. Our study collects data on a plethora of lifestyle factors during a lengthy baseline interview averaging four hours, which might deter older women or women with more advanced disease from participating.…”

Section: Discussionmentioning

confidence: 99%

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The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California

Kwan

Ambrosone

Lee

et al. 2008

Cancer Causes Control

106

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Objective-With 2.3 million breast cancer survivors in the U.S. today, identification of modifiable factors associated with breast cancer recurrence and survival is increasingly important. Only recently new studies have been designed to examine the impact of lifestyle factors on prognosis, including Pathways, a prospective study of women with breast cancer in Kaiser Permanente Northern California (KPNC).Methods-Pathways aims to examine the effect on recurrence and survival of 1) lifestyle factors such as diet, physical activity, quality of life, and use of alternative therapies and 2) molecular factors such as genetic polymorphisms involved in metabolism of chemotherapeutic agents. Eligibility includes any woman diagnosed with invasive breast cancer within KPNC, no previous diagnosis of other invasive cancer, age 21 years or older, and ability to speak English, Spanish, Cantonese, or Mandarin. Newly-diagnosed patients are identified daily from electronic pathology records and are enrolled within two months of diagnosis. An extensive baseline interview is conducted, blood and saliva samples are collected, and body measurements are taken. Women are followed for lifestyle updates, treatment, and outcomes by self-report and query of KPNC databases.Results-Recruitment began in January 9, 2006, and as of January 16, 2008, 1,539 women have been enrolled along with collection of 1,323 blood samples (86%) and 1,398 saliva samples (91%). Conclusions-ThePathways Study will become a rich resource to examine behavioral and molecular factors and breast cancer prognosis.

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Section: Discussionmentioning

confidence: 99%

“…96 (28) 173 (37) 150 (35) 97 (32) 516 (34) 766 (31) Unknown 21 (6) 49 (10) 36 (8) 23 (8) 129 (8) 218 (9) KP Service Area d…”

Section: Discussionunclassified

The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California

Kwan

Ambrosone

Lee

et al. 2008

Cancer Causes Control

106

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“…Both of them restricted inclusion to early stage breast cancer. While merely three large cohort studies of breast cancer patients are collecting data [7][8][9].…”

Section: Discussionmentioning

confidence: 99%

“…The Shanghai Breast Cancer Survival (SBSS) Study comprises 2,236 Chinese women with breast cancer and collects information on lifestyle related factors and diseaseand treatment related factors [9].…”

Section: Search Strategy and Selection Criteriamentioning

confidence: 99%

Lifestyle changes and breast cancer prognosis: a review

Kellen

Vansant

Christiaens

et al. 2008

Breast Cancer Res Treat

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“…The QOL assessment provided by this instrument has been shown to have satisfactory levels of reliability and validity, 22,23 and its utility among breast cancer patients has been previously described. 24,25 The inventory comprises 74 items that can be classified into 20 facets that are then categorized into a global health status/QOL assessment and the following four domains: (1) physical well-being (sleep and energy, pain and physical discomfort, eating functioning, sexual functioning, sensory functioning, and capability of daily living), (2) psychological well-being (psychological distress, negative feelings, positive feelings, cognitive functioning, and body/ self-image), (3) social well-being (social support, interpersonal relationships, work and study capacity, recreational and leisure activities, and marriage and family), and (4) material well-being (housing situation, community services, living environment, and financial situation). Patients' responses were converted to a score of 0 to 100 on each domain and facet, with higher scores reflecting higher QOL.…”

Section: Qol Assessmentmentioning

confidence: 99%

Quality of Life After Breast Cancer Diagnosis and Survival

Epplein

Zheng²,

Wang³

et al. 2011

JCO

Self Cite

159

128

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A B S T R A C T PurposeTo examine the association of quality of life (QOL) after diagnosis of breast cancer with mortality and recurrence. Patients and MethodsFrom 2002 to 2004, a total of 2,230 breast cancer survivors completed the General Quality of Life Inventory-74 6 months after diagnosis as part of the Shanghai Breast Cancer Survivor Study. Also collected at baseline was information on demographic and clinical characteristics. At 36 months postdiagnosis, 1,845 of these women were re-evaluated for QOL. Outcomes were ascertained by in-person interview and record linkage to the vital statistics registry. The association of QOL with total mortality and cancer recurrence was assessed by using Cox regression analysis. ResultsDuring a median follow-up of 4.8 years after the 6-month postdiagnosis QOL assessment, 284 deaths were identified. Recurrence was documented in 267 patients after 108 patients with stage IV breast cancer or recurrence before study enrollment were excluded. Women with the highest tertile of social well-being QOL score, compared with those with the lowest score, had a 38% decreased risk of mortality (95% CI, 0.46 to 0.85; P for trend ϭ .002) and a 48% decreased risk of breast cancer recurrence (95% CI, 0.38 to 0.71; P for trend Ͻ .001). QOL assessed at 36 months postdiagnosis was not significantly associated with subsequent risk of mortality or recurrence. ConclusionSocial well-being in the first year after cancer diagnosis is a significant prognostic factor for breast cancer recurrence or mortality, suggesting a possible avenue of intervention by maintaining or enhancing social support for women soon after their breast cancer diagnosis to improve disease outcomes.

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Impact of newly diagnosed breast cancer on quality of life among Chinese women

Abstract: The findings of the present study provide important information on QOL and their correlates among Chinese women with newly diagnosed breast cancer and are helpful in developing treatment strategies accordingly.

Cited by 51 publications

References 49 publications

The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California

The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California

Lifestyle changes and breast cancer prognosis: a review

Quality of Life After Breast Cancer Diagnosis and Survival

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