Impact of Periodontal Disease on Late Morbimortality (10 Years) of Pacientes with
            Acute Coronary Syndrome

Moras, Luis Lemos; Carvalho, Thamara Angeliny; Oliveira, Marina Bragheto; Ricci, Gabriel Andrey; Accarini, Renata; Godoy, Moacir Fernandes de

doi:10.5935/2359-4802.20180074

Cited by 3 publications

(5 citation statements)

References 2 publications

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“…Essa bacteremia causada pelos patógenos periodontais interage com os anticorpos do hospedeiro, induzindo reações inflamatórias. Nos dados obtidos pelo estudo, dos 32.000 participantes houve um aumento em 25% no risco relativo à doença cardiovascular entre paciente com periodontite (Moras et al, 2019).…”

Section: Resultsunclassified

O tratamento periodontal e a prevenção de doenças cardiovasculares: revisão integrativa da literatura

Campos

Cardoso

Monteiro

et al. 2023

RSD

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As doenças periodontais (DPs) estão entre as doenças inflamatórias mais prevalentes e possuem etiologia de infecções microbianas. Estudos revelam a possibilidade de associação entre inflamações locais e outros órgãos do corpo, favorecendo a disseminação de patógenos bucais. O objetivo do estudo foi realizar uma revisão integrativa, no intuito de discutir a relevância do tratamento periodontal como aliado na prevenção de doenças cardiovasculares (DVCs) e como tratamento auxiliar dessas doenças. Para isso, foi realizada uma coleta de dados utilizando os dos descritores em inglês e português: (“doença cardiovascular e doença periodontal”; “doença cardiovascular e doença periodontal e inflamação”; doença cardiovascular e doença periodontal e prevenção”) com recorte entre os anos 2017-2022. Após estabelecidos critérios de inclusão (estudos em humanos, independente do sexo, estudos clínicos, observacionais, metanálises, revisões sistemáticas, publicações nos idiomas português, inglês e espanhol) e exclusão (artigos com outras abordagens sobre as DPs e as DCVs diferentes dos aspectos da prevenção das DPs), os artigos foram selecionados para análise. Os resultados revelaram 52 artigos que, após a exclusão dos estudos: apresentavam fuga de tema, não respondiam à questão de investigação ou estavam duplicados, resultando em um total de 26 artigos. O presente estudo ressaltou que a maioria das pesquisas apontam para uma associação entre a periodontite apical e a doença cardiovascular, destacando a necessidade de abordagem do assunto na formação profissional do cirurgião-dentista e a importância de pesquisas clínicas que corroboram com estudos já existentes, favorecendo maior elucidação do tema e maior desenvolvimento em manejo de casos clínicos.

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Section: Resultsunclassified

O tratamento periodontal e a prevenção de doenças cardiovasculares: revisão integrativa da literatura

Campos

Cardoso

Monteiro

et al. 2023

RSD

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“…Seven papers were duplicated across different databases and were also excluded. Applying inclusion and exclusion criteria, 29 publications were excluded during screening, and nine exclusions occurred during the eligibility phase, which resulted in 34 remaining studies 5,6,8,12–42 (Table 1). Reference lists checking did not yield in new inclusions.…”

Section: Resultsmentioning

confidence: 99%

“…These variables were not present in unfavorable opinions. Genetic variables and mortality were found exclusively in favorable opinions; however, these last two variables were the least frequent in included publications, occurring only in one article 42 for mortality (2.94%) and three articles 5,12,18 for genetic variables (8.82%). Nevertheless, a statistically significant result was not found between the opinions of the studies and the variables, indicating in the context of this scoping review that the variables were not able to influence the opinions of analyzed studies.…”

Section: Discussionmentioning

confidence: 98%

“…Considering the parameters of evidence, for the researched period of time, observational studies 6,8,[12][13][14]16,18,19,[22][23][24][25][26][27][28][29][30][31][33][34][35][36][40][41][42] comprised 73.53% of included studies in the present scoping review, which could be classified as of level II-2 if there were multicentric studies, which did not occur. The analyzed controlled clinical trials, 17,20,21,38,39 which could show level of evidence II-1, were also compromised because two systematic reviews of controlled clinical trials 15,37 were uncertain regarding the relation between PD and CAD, as well as demonstrated a high risk of bias of analyzed studies.…”

Section: Discussionmentioning

confidence: 99%

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Is there evidence that periodontal diseases are risk factors for coronary arterial disease?—Scoping review

Silva

Aguiar

Gomes

et al. 2020

Special Care in Dentistry

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Aim: To determine the scientific evidence regarding the condition of periodontal diseases (PDs) as risk factors of coronary artery diseases. Materials and methods:A scoping review was performed through the selection of articles from online databases (Medline via PubMed, LILACS, and Cochrane CENTRAL), using a search algorithm and eligibility criteria for data extraction and data synthesis of included papers. Four hundred forty-one studies from online databases and 1364 from reference lists were initially identified, and 34 articles were selected for inclusion. Articles had to be published between 2015 and 2020 and had to associate PDs to coronary arterial diseases. All studies comprised a sample of 446443 participants. Favorable opinions totaled 70.59%, and the cross-sectional observational study design was more frequently found (32.35%). Biochemical outcomes were showed more frequently, such as inflammatory biomarkers (58.82%). Despite a large advantage for favorable opinions, a statistically significant result was not found when extracted data were combined with studies opinions. Conclusion:The evidence was classified as level II-3, hence, still distant from the best ranks and can therefore be considered as unclear. Moreover, studies with the higher potential to generate evidence showed a high risk of bias.

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“…2,3 The presence of the PD is correlated with more severe cardiovascular disease and recurrences, with a poor outcome based on recent data. 4 Thus, an accurate PD screening in patients with cardiovascular diseases would be of great im-portance for an early diagnosis and adequate treatment to reduce cardiovascular recurrences in young adults.…”

mentioning

confidence: 99%

Is Periodontal Disease a Risk Factor for Recurrent Coronary Events?

Biriș

Rodean

Halațiu

et al. 2021

Journal of Interdisciplinary Medicine

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Impact of Periodontal Disease on Late Morbimortality (10 Years) of Pacientes with Acute Coronary Syndrome

Cited by 3 publications

References 2 publications

O tratamento periodontal e a prevenção de doenças cardiovasculares: revisão integrativa da literatura

O tratamento periodontal e a prevenção de doenças cardiovasculares: revisão integrativa da literatura

Is there evidence that periodontal diseases are risk factors for coronary arterial disease?—Scoping review

Is Periodontal Disease a Risk Factor for Recurrent Coronary Events?

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