Background: Approximately 130 000 cases of cervical cancer are diagnosed every year in China, and its incidence rate ranks second among all gynecologic tumors.These patients are more likely to have poor sleep quality than healthy controls.
Aims:To evaluate the efficacy of mindfulness-based stress reduction on objective and subjective sleep parameters and hypnotic medication use in patients with insomnia secondary to cervical cancer.
Methods and Results: This randomized controlled trial enrolled patients with insomnia that was caused or worsened by cervical cancer. Seventy patients with insomnia caused or aggravated by cervical cancer were randomly divided into either a usual care group or an 8-week mindfulness-based stress reduction group. Subjective sleep parameters, objective sleep parameters, and hypnotic medication consumption were assessed at baseline, after the program, and 6 and 12 months after completing the interventions. The results suggested that mindfulness-based stress reduction had a positive effect on subjective sleep parameters (total wake time: Δ = 45.32, P < .05; sleep efficacy: Δ = 6.87, P < .05; total sleep time: Δ = 22.22, P < .01; and insomnia severity index: Δ = 7.36, P < .05), and these positive effects were also observed at 6 and 12 months after completing the interventions. However, the objective sleep parameters (such as polysomnography and actigraphy) were not significantly improved. There were no associations between the subjective sleep parameters and the objective sleep parameters. The effect of the mindfulnessbased stress reduction intervention on the reduction of the dosage of hypnotic medications was limited to 6 months, and no long-term effect was observed.Conclusion: Mindfulness-based stress reduction had a positive effect on subjective sleep parameters of patients with insomnia secondary to cervical cancer. Its effect on the reduction the dosage of hypnotic medications was limited to 6 months, and no long-term effect was observed.