Implantation de chondrocytes autologues pour lésions cartilagineuses du sujet jeune. Étude de 24 cas*

Bahuaud, J; Maitrot, R. C.; Bouvet, R; Kerdiles, N.; Tovagliaro, F.; Synave, J; Buisson, P.; Thierry, J.; Versier, A; Romanet, Jean-Paul; Chauvin, F.; Gillet, J. P.; Allizard, J.P.; Belenet, H de

doi:10.1016/s0001-4001(99)80005-1

Cited by 31 publications

(13 citation statements)

References 3 publications

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“…Aspects of patient heterogeneity and quality classification are shown in Table 2. 42,45,46,[50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67] To date, relatively few patients have been followed for an adequate period of time (> 2 years). Ten randomised controlled trials (RCTs), proposed or currently underway, comparing ACT with other interventions were also identified ( Table 3).…”

Section: Quantity and Quality Of Researchmentioning

confidence: 99%

“…Of these, 17 reports met inclusion criteria. 42,45,46,[50][51][52][53][54][55][56][57][58][59][60][61][62][63][64] For completeness, a key study by Peterson and colleagues 61,62 is listed twice in the results tables in order to highlight more recent data available in abstract form only. Eight other studies were available as abstracts only.…”

Section: Quantity and Quality Of Researchmentioning

confidence: 99%

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Effectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review

Jobanputra

Parry

Fry‐Smith

et al. 2001

Health Technol Assess

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents, York Publishing Services by:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS and public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please contact York Publishing Services at the address above. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to York Publishing Distribution and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.ncchta.org/htacd.htm). Or contact York Publishing Services (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTAEffectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review This report should be referenced as follows:Jobanputra P, Parry D, Fry-Smith A, Burls A. Effectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review. Health Technol Assess 2001;5(11).Health Technology Assessment is indexed in Index Medicus/MEDLINE and Excerpta Medica/ EMBASE. Copies of the Executive Summaries are available from the NCCHTA website (see opposite). NHS R&D HTA ProgrammeT he NHS R&D Health Technology Assessment (HTA) Programme was set up in 1993 to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS.The research reported in this monograph was commissioned by the HTA Programme on behalf of the National Institute for Clinical Excellence (NICE). Rapid reviews are completed in a limited time to inform the appraisal and guideline development processes managed by NICE. The review brings together evidence on key aspects of t...

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Section: Quantity and Quality Of Researchmentioning

confidence: 99%

Section: Quantity and Quality Of Researchmentioning

confidence: 99%

Effectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review

Jobanputra

Parry

Fry‐Smith

et al. 2001

Health Technol Assess

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“…The technical difficulty and need for a relatively large arthrotomy associated with the traditional ACI procedure as well as a desire to improve the subsequent repair tissue have spurred the desire to develop an easier, more effective method of implanting cultured chondrocytes into the knee joint[41,45]. The principle is to culture autologous cells onto a three dimensional biocompatible scaffold, which is then implanted into the defect (Figure 1).…”

Section: Maci Proceduresmentioning

confidence: 99%

“…Expansion of chondrocytes is generally performed in monolayer culture to obtain fifteen to twenty million cells over about four weeks. A few days before implantation, the expanded chondrocytes are seeded onto a biodegradable scaffold [41]. A common problem in monolayer expansion of chondrocytes is the dedifferentiation of cells.…”

Section: Maci Proceduresmentioning

confidence: 99%

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MACI - a new era?

Jacobi

Villa

Magnussen

et al. 2011

BMC Sports Sci Med Rehabil

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Full thickness articular cartilage defects have limited regenerative potential and are a significant source of pain and loss of knee function. Numerous treatment options exist, each with their own advantages and drawbacks. The goal of this review is to provide an overview of the problem of cartilage injury, a brief description of current treatment options and outcomes, and a discussion of the current principles and technique of Matrix-induced Autologous Chondrocyte Implantation (MACI). While early results of MACI have been promising, there is currently insufficient comparative and long-term outcome data to demonstrate superiority of this technique over other methods for cartilage repair.

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Harnessing the Versatility of Bacterial Collagen to Improve the Chondrogenic Potential of Porous Collagen Scaffolds

Parmar

St-Pierre

Chow

et al. 2016

Adv Healthcare Materials

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Collagen I foams are used in the clinic as scaffolds to promote articular cartilage repair as they provide a bioactive environment for cells with chondrogenic potential. However, collagen I as a base material does not allow for precise control over bioactivity. Alternatively, recombinant bacterial collagens can be used as “blank slate” collagen molecules to offer a versatile platform for incorporation of selected bioactive sequences and fabrication into 3D scaffolds. Here, we show the potential of Streptococcal collagen-like 2 (Scl2) protein foams modified with peptides designed to specifically and noncovalently bind hyaluronic acid and chondroitin sulfate to improve chondrogenesis of human mesenchymal stem cells (hMSCs) compared to collagen I foams. Specific compositions of functionalized Scl2 foams lead to improved chondrogenesis compared to both nonfunctionalized Scl2 and collagen I foams, as indicated by gene expression, extracellular matrix accumulation, and compression moduli. hMSCs cultured in functionalized Scl2 foams exhibit decreased collagens I and X gene and protein expression, suggesting an advantage over collagen I foams in promoting a chondrocytic phenotype. These highly modular foams can be further modified to improve specific aspects chondrogenesis. As such, these scaffolds also have the potential to be tailored for other regenerative medicine applications.

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Implantation de chondrocytes autologues pour lésions cartilagineuses du sujet jeune. Étude de 24 cas*

Cited by 31 publications

References 3 publications

Effectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review

Effectiveness of autologous chondrocyte transplantation for hyaline cartilage defects in knees: a rapid and systematic review

MACI - a new era?

Harnessing the Versatility of Bacterial Collagen to Improve the Chondrogenic Potential of Porous Collagen Scaffolds

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