An expression for the free energy of an (001) oriented domain wall of the anisotropic 3D Ising model is derived. The order-disorder transition takes place when the domain wall free energy vanishes. In the anisotropic limit, where two of the three exchange energies (e.g. J x and J y ) are small compared to the third exchange energy (J z ), the following asymptotically exact equation for the critical temperature is derived, sinh(2J z /k B T c )sinh(2(J x þ J y )/k B T c )) ¼ 1. This expression is in perfect agreement with a mathematically rigorous result Griffiths and Fisher (Phys. Rev. 162, 475 (1967)) using an approach that relies on a refinement of the Peierls argument. The constant that was left undetermined in the Weng et al. result is estimated to vary from $0.84 at ((H x þ H y )/H z ) ¼ 10 À2 to $0.76 at ((H x þ H y )/H z ) ¼ 10 À20 .