The authors predicted streamflow in an urban–rural watershed using a nested regional–local modeling approach for the community of Manchester, Iowa, which is downstream of a largely rural watershed. The nested model coupled the hillslope-link model (HLM), used to simulate the upstream rural basins, and XPSWMM, which was used to simulate the more complex rainfall–runoff dynamics and surface and subsurface drainage in the urban areas, making it capable of producing flood maps at the street level. By integrating these models built for different purposes, we enabled fast and accurate simulation of hydrological processes in the rural basins while also modeling the flows in an urban environment. Using the model, we investigated how the spatial and temporal resolution of radar rainfall inputs can affect the modeled streamflow. We used a combination of three radar rainfall products to capture the uncertainty of rainfall estimation in the model results. Our nested model was able to simulate the hydrographs and timing and duration above the threshold known to result in nuisance flooding in Manchester. The spatiotemporal resolution the radar rainfall input to the model impacted the streamflow outputs of the regional, local, and nested models differently depending on the storm event.