Improving the Biocompatibility of Implantable Bioelectronics Devices

Slaughter, Gymama

doi:10.1002/9783527673148.ch13

Cited by 3 publications

(1 citation statement)

References 127 publications

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“…In addition, implantable bioelectronic power sources use biomaterials to enhance the biocompatibility, longevity and corrosion protection of the implantable devices from the harsh environments of the body [ 16 , 17 , 18 ] without adverse side effects. The body is an extremely corrosive environment because of cations such as Na + , K + , Ca + , Mg + , anions such as chloride, bicarbonate, phosphate, and large amounts of dissolved oxygen found throughout the body [ 19 , 20 , 21 ].…”

Section: Introductionsmentioning

confidence: 99%

Corrosion Protection of Al/Au/ZnO Anode for Hybrid Cell Application

Slaughter

Stevens

2015

Membranes

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Effective protection of power sources from corrosion is critical in the development of abiotic fuel cells, biofuel cells, hybrid cells and biobateries for implantable bioelectronics. Corrosion of these bioelectronic devices result in device inability to generate bioelectricity. In this paper Al/Au/ZnO was considered as a possible anodic substrate for the development of a hybrid cell. The protective abilities of corrosive resistant aluminum hydroxide and zinc phosphite composite films formed on the surface of Al/Au/ZnO anode in various electrolyte environments were examined by electrochemical methods. The presence of phosphate buffer and physiological saline (NaCl) buffer allows for the formation of aluminum hyrdroxide and zinc phosphite composite films on the surface of the Al/Au/ZnO anode that prevent further corrosion of the anode. The highly protective films formed on the Al/Au/ZnO anode during energy harvesting in a physiological saline environment resulted in 98.5% corrosion protective efficiency, thereby demonstrating that the formation of aluminum hydroxide and zinc phosphite composite films are effective in the prevention of anode corrosion during energy harvesting. A cell assembly consisting of the Al/Au/ZnO anode and platinum cathode resulted in an open circuit voltage of 1.03 V. A maximum power density of 955.3 μW/ cm2 in physiological saline buffer at a cell voltage and current density of 345 mV and 2.89 mA/ cm2, respectively.

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