In-Vitro Anthelmintic Activity of Aerial Roots of Ficus Benghalensis

Abstract

<p>Helminth infections are among the most widespread infections in humans.<em> Ficus benghalensis</em> L.</p> <p>(Moraceae) is traditionally used in Indian system of medicine. Anthelmintic activity was evaluated using worms as experimental models<em>.</em> Test sample of <em>Ficus benghalensis</em> aerial roots extracts was prepared at the concentration 10, 25, 50mg/ml in normal saline solution. Standard drug used Albendazole (20mg/ml). Time for death of worms were recorded after ascertaining that worms neither moved when shaken vigorously nor when dipped in warm water (50^o c). Phytochemical constituents such as Phenolics, tannins, saponins, mucilage and alkaloids may be responsible for the anthelmintic activity. It may be concluded that methanolic extract of <em>Ficus benghalensis </em>possesses significant anthelmintic property.</p

Ficus benghalensis—A comprehensive review on pharmacological research, nanotechnological applications, and patents

“…On the contrary, no paralysis or death occurred in the control groups during the given period (Bhardwaj et al, 2012). Tuse et al (2011), investigated methanolic extract of aerial roots using the above approach of paralyzing or killing Indian earthworms at 10, 20, and 50 mg/ml, and a dose-dependent activity was reported. Meanwhile, another study investigated the comparative anthelmintic activity of latex of F. religiosa, F. elastica, and F. benghalensis, and reported potent activity by F. benghalensis latex extract, which took 10.2 and 13.4 minutes for paralysis and 26.3 and 30.1 to completely kill the earthworm at 250 and 500 μl/ml dose levels, respectively.…”

Evaluation of in-vitro Anthelmintic Activity of Ximenia americana, Hopea ponga and Vitex leucoxylon

“…4 Anthelmintic drugs can be classified according to their chemical structure as well as their specific action towards specific type of the helminthes. 5 Because of the increasing toxicity and allergic manifestations of anthelmintic drugs the gastrointestinal helminthes became resistant to current available synthetic anthelmintic drugs 6,7 From ancient time medicinal plants play important role in the elimination of soil transmitted Helminthiasis. Natural products based drugs have used against various diseases since time immemorial.…”