In vitro antibacterial activity of Hibiscus rosa–sinensis flower extract against human pathogens

Potential Antibacterial Activity of Hibiscus rosasinensis Linn Flowers Extracts

“…All bacteria represent increasing in inhibition zone diameter with increasing of methanol extract concentration. Among all treatment, highest zone inhibition observed from flower methanol extract at concentration 1mg/ml, for E. coli (27±0.12) mm, this finding agree with Al-Alak et al, 2015;Ruban andGajalakshmi, 2012 andKumar et al, 2010), followed by Staphylococcus aureus with (21±0.41)mm inhibition zone at the same flower extract concentration (Figure 1 and 2). Methanol extract at high concentration (1mg/ml) showed maximum inhibition zone against E. coli, Staphylococcus aureus and Streptococcus pyogenes as (27±0.12, 21±0.41, and 18±0.65) mm, followed by 0.5 mg/ml methanol extract showed maximum inhibition zone against E. coli as (17±o.21) mm, this finding in agree with the finding of (Uddin et al, 2010), reported that the methanolic extract of hibiscus flower obtain antibacterial effect at high concentration.…”

“…Its medicinal values have been mentioned in traditional folk medicines for variety of diseases. Recent studies shown that Hibiscus rosasinensis extract from different part of plant has significant protective effects (Shivananda et al, 2007;Ruban and Gajalakshmi, 2012;Salem et al, 2013;Kannathasan et al, 2011 andMohamed et al, 2014), thus these plants have great medicinal potential for the therapy of infection. Flowers and leaves are found to possess antioxidant, antifungal, anti-infectious, antimicrobial, antiinflammatory, anti-diarrheic and antipyretic activity (David and Leonard, 1998).…”

Anticestodal properties of Hibiscus rosa-sinensis L. (Malvaceae): an in vitro and in vivo study against Hymenolepis diminuta (Rudolphi, 1819), a zoonotic tapeworm

“…In experimental studies, the leaves and flowers of H. rosa-sinensis have been demonstrated to aid in healing of ulcers (Kurup et al 1979). More recently, it has also been demonstrated through controlled experimentations that various parts of this plant also possess cardioprotective (Gauthaman et al 2006), antibacterial (Ruban and Gajalakshmi 2012) and antioxidant (Sarkar et al 2014) activities.…”

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“…1 Scientific interest in medicinal plants has flourished due to an increased efficiency of new plant derived drugs, growing interest in natural products and rising concerns about the side effects of conventional medicine. The use of various herbal remedies and preparations are described throughout human history representing the origin of modern medicine.…”