In Vitro Antioxidant Activity of Extracts from Fruits of Muntingia calabura Linn. from India

Preethi, Kathirvel; Vijayalakshmi, N.; Shamna, R.; Sasikumar, J. M.

doi:10.1016/s0975-3575(10)80065-3

Cited by 34 publications

(29 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, no concentration of extract was given in this study, which made the validation of AEMC L antioxidant activity less convincing. Furthermore, Preethi et al (2010) reported on the antioxidant potential of various extracts of M. calabura fruits (e.g., MEMC Fr , HEMC Fr , EAEMC Fr , CEMC Fr , and BEMC Fr ) should also be interpreted with cautious despite the results obtained using various models of antioxidant assays. In the DPPH-, superoxide anion-, hydroxyl-, nitric oxide-radical scavenging assay, all extracts exerted antioxidant effect with the recorded IC 50 values ranging between 90.0 and 351.0, 79.0 and 379.0, 49.0 and 281.0, and 187.0 and 498.0 mg/mL in comparison with BHT, which recorded the respective IC 50 of 26.0, 83.0, 41.0, and 33.0 mg/mL.…”

Section: Discussionmentioning

confidence: 99%

“…The IC 50 value recorded for MEMC L (22.0 mg/mL) and ascorbic acid (the reference drug; 10 mg/mL) was 30 mg/mL and, thus, fulfilled the FDA requirement. Taking into account that the ascorbic acid produced an IC 50 value that is approximately two-fold lower than that of the BHT (12 mg/mL versus 26 mg/ mL) when assessed using the DPPH radical scavenging assay, it is suggested that Preethi et al (2010) should have used more than one reference drug (e.g., ascorbic acid) for the comparison purposes. Unfortunately, adding the number of reference drugs will not help to contradict the fact that the fruits and its extracts did not meet the FDA requirements to be considered effective antioxidants due to the high IC 50 recorded.…”

Section: Discussionmentioning

confidence: 99%

“…Three years later, Preethi et al (2010) investigated the antioxidant activity of fully ripened fruits M. calabura. The fruits, collected between May and June, 2008 from Erode District, Tamil Nadu, India, were prepared as hexane (HEMC Fr ), chloroform (CEMC Fr ), ethyl acetate (EAEMC Fr ), butanol (BEMC Fr ), and methanol (MEMC Fr ) extracts and subjected to several antioxidant assays such as total phenolic content (TPC), DPPH radical scavenging activity, reductive ability, superoxide anion-, hydroxyl ion (''OH) radical-and nitric oxide-scavenging activity, ferric ion chelating activity, and lipid peroxidation reduction assays.…”

Section: Antioxidant Activitymentioning

confidence: 99%

See 2 more Smart Citations

Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations

Mahmood

Nasir

Rofiee

et al. 2014

Pharmaceutical Biology

View full text Add to dashboard Cite

Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or ''kerukup siam'' in Malay, have been reported to possess medicinal value, supported by a number of scientific studies. Objective: To gather all information related to the ethnomedicinal uses, phytochemical compositions, and pharmacological activities of M. calabura and present them as a comprehensive and systematic review article. Materials and methods: Literature has been retrieved from a number of databases (e.g., Pubmed, Science Direct, Springer Link, etc.). General web searches were also carried out using Google and Yahoo search engines by applying some related search terms (e.g., Muntingia calabura, phytochemical, pharmacological, extract, and traditional uses). The articles related to agriculture, ecology, and synthetic work and those using languages other than English or Malay have been excluded. The bibliographies of papers relating to the review subject were also searched for further relevant references. Results and discussion: The literature search conducted using the above-mentioned Internet search engines only lead to the identification of 36 journals published as early as 1987. From the articles reviewed, M. calabura possessed various pharmacological activities (e.g., cytotoxic, antinociceptive, antiulcer, anti-inflammatory), which supported the folklore claims and could be attributed to its phytoconstituents. Conclusion: Muntingia calabura possesses remarkable medicinal value, which warrants further and in-depth studies. Therefore, this review paper is presented to help guide researchers to plan their future studies related to this plant in the hope of isolating potential leads for future drug development.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Antioxidant Activitymentioning

confidence: 99%

See 1 more Smart Citation

Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations

Mahmood

Nasir

Rofiee

et al. 2014

Pharmaceutical Biology

View full text Add to dashboard Cite

show abstract

“…Estudos preliminares também relataram o elevado conteúdo de compostos fenólicos da calabura. Frutos cultivados na Índia apresentaram teores de compostos fenólicos entre 358,00 e 1486,00 mg 100g -1 de fruto fresco (PREETHI et al, 2010), enquanto que para a polpa foram observados valores de 133,40 a 387,20 mg 100 g -1 (KOLAR; KAMBLE; DIXIT, 2011). A variação do conteúdo de compostos fenólicos no fruto de calabura ocorre devido à diversos fatores agrícolas de cultivo, manejo e clima.…”

Section: Análisesunclassified

“…A variação do conteúdo de compostos fenólicos no fruto de calabura ocorre devido à diversos fatores agrícolas de cultivo, manejo e clima. Além disso, a técnica de extração, o solvente empregado e a metodologia analítica influenciam no resultado final da análise (PREETHI et al, 2010;KOLAR;KAMBLE;DIXIT, 2011).…”

Section: Análisesunclassified

Physicochemical characterization and antioxidant activity of Calabura fruit (Muntingia calabura L.)

et al. 2016

View full text Add to dashboard Cite

The objective of this work was to determine the physical and physicochemical characteristics, proximate composition, antioxidant activity, total phenolic compounds, vitamin C content and total anthocyanins of different fractions of the calabura fruits (peel, pulp and whole fruit). The fruits showed average diameter and weight of 14.50 mm and 1.57 g, respectively, and high yield in pulp (75.38%). The whole fruit showed: pH (5.64), titratable acidity (0.11 g citric acid 100 g-1), soluble solids (10.24 °Brix), ratio (93.76), moisture (77.36%), ash (5.65%), lipids (7.79%), proteins (8.29%), crude fiber (5.93%), carbohydrates (72.15%), vitamin C (3.30 mg 100 g-1), phenolic compounds (526.55 mg tannic acid equivalents (TAE) 100 g-1), anthocyanins (4.08 mg cyanidin-3-glucoside equivalents (CGE) 100 g-1) and DPPH IC50 (82.25 μg mL-1).The peel showed high antioxidant activity (82.00 μg mL-1) due to the highest contents of phenolic compounds (868.90 mg TAE 100 g-1), anthocyanins (3.87 mg CGE 100 g-1) and vitamin C (4.20 mg 100 g-1). In conclusion, the calabura fruit showed high content of bioactive compounds with antioxidant properties in vitro.

show abstract

Muntingia calabura

Lim¹

2011

Edible Medicinal and Non Medicinal Plants

View full text Add to dashboard Cite

show abstract

In Vitro Antioxidant Activity of Extracts from Fruits of Muntingia calabura Linn. from India

Cited by 34 publications

References 23 publications

Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations

Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations

Physicochemical characterization and antioxidant activity of Calabura fruit (Muntingia calabura L.)

Muntingia calabura

Contact Info

Product

Resources

About