In vitro antioxidant study of polyphenol from red seaweeds dichotomously branched gracilaria Gracilaria edulis and robust sea moss Hypnea valentiae

Mahendran, S.; Maheswari, P. Uma; Sasikala, V; Rubika, Jeba jaya; Pandiarajan, Jeyaraj

doi:10.1016/j.toxrep.2021.07.006

Cited by 38 publications

(13 citation statements)

References 38 publications

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“…In addition, signals specific to aromatic rings were observed, such as the band at 1693 cm −1 corresponding to C=C stretching, the signal at 1453 cm −1 is due to C-C stretching and, finally, the signal at 1034 cm −1 is attributed to C-O stretching. All these bands show the presence of polyphenols in the extract obtained [ 29 , 30 , 31 ].…”

Section: Resultsmentioning

confidence: 99%

Sargassum filipendula, a Source of Bioactive Compounds with Antioxidant and Matrix Metalloproteinases Inhibition Activities In Vitro with Potential Dermocosmetic Application

et al. 2023

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The antioxidant and the potential inhibitory capacity of matrix metalloproteinases of the phlorotannin-type polyphenolic and fucoidan-type polysaccharides extracts obtained from the macroalga S. filipendula were evaluated. Through chromatographic and spectroscopic techniques, the corresponding chemical structure of compounds present in the extracts was determined. Antioxidant capacity was evaluated using the methyl linoleate model for the inhibition of lipid peroxidation, and the free radical scavenging capacity was assessed using DPPH, ABTS, •OH, O2•− methods. The matrix metalloproteinase inhibition potential was measured by collagenase and elastase inhibition tests, using epigallocatechin gallate as a positive control. The extracts exhibited a high scavenging capacity of radical species evaluated and inhibition of diene conjugate formation and thiobarbituric acid reactive substances. The results showed that the crude extracts presented dose-dependent collagenase and elastase inhibition, with IC50 values between 0.04 and 1.61 mg/mL. The structure of the residues of the polysaccharide was identified mainly as (1→3)-sulfated (1→3) α-l-fucopyranose at carbon 4 and residues of β-d-glucopyranose, α-d-Mannopyranose, and β-d-Galactopyranose, while in the polyphenol extract the presence of phloroglucinol was identified and the presence of eckol, bifuhalol, and trifuhalol was suggested. Our results allow us to infer that S. filipendula is a potential source of bioactive ingredients with antioxidant and anti-aging activity.

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Section: Resultsmentioning

confidence: 99%

Sargassum filipendula, a Source of Bioactive Compounds with Antioxidant and Matrix Metalloproteinases Inhibition Activities In Vitro with Potential Dermocosmetic Application

et al. 2023

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“…Polyphenols from red algae carry potential assets, as they may have a strong pharmaceutical value in the future. Biochemical analysis revealed the presence of flavonoids, saponins, tannin, and steroids in both red algae, while only G. edulis revealed phenolics and alkaloids [ 71 ].…”

Section: Antimicrobial Activity From Rhodophyta and Chlorophyta Extractsmentioning

confidence: 99%

An Overview on Antimicrobial Potential of Edible Terrestrial Plants and Marine Macroalgae Rhodophyta and Chlorophyta Extracts

Lomartire

Gonçalves

2023

Marine Drugs

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Antibiotics are used to prevent and treat bacterial infections. After a prolonged use of antibiotics, it may happen that bacteria adapt to their presence, developing antibiotic resistance and bringing up health complications. Nowadays, antibiotic resistance is one of the biggest threats to global health and food security; therefore, scientists have been searching for new classes of antibiotic compounds which naturally express antimicrobial activity. In recent decades, research has been focused on the extraction of plant compounds to treat microbial infections. Plants are potential sources of biological compounds that express several biological functions beneficial for our organism, including antimicrobial activity. The high variety of compounds of natural origin makes it possible to have a great bioavailability of antibacterial molecules to prevent different infections. The antimicrobial activity of marine plants, also called seaweeds or macroalgae, for both Gram-positive and Gram-negative, and several other strains infective for humans, has been proven. The present review presents research focused on the extraction of antimicrobial compounds from red and green macroalgae (domain Eukarya, kingdom Plantae). Nevertheless, further research is needed to verify the action of macroalgae compounds against bacteria in vitro and in vivo, to be involved in the production of safe and novel antibiotics.

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“…It was previously reported that the TPC of Fucus spiralis could be as high as 1.15 ± 0.06 mmol GAE/g dry weight, which is equivalent to 195.6 ± mg.GAE/g extract [28]. In light of the previous studies and evidence, it appears that the natural phenolic grouped compounds in flavonoids show anticancer, anti-inflammatory, antihypertensive, antioxidative, and antiproliferative properties [29][30][31].…”

Section: Phytochemical Test Of P Hornemanniimentioning

confidence: 99%

Bioactive compounds of Marine Red algae Portieria hornemannii and its bio control effects against Culex quinquefasciatus Dengue vectors

2022

pnr

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The red seaweed Portieria hornemannii was investigated for phytochemicals, yield of extract, and total flavonoids and phenol content. Methanol and chloroform were used to extract metabolites from P. hornemannii. Methanol extract from P. hornemannii (MEPH) performed superior to chloroform in the phytochemical test. Purified by 86%, the crude methanol extract is subjected to a quantitative method, which determined its total phenol content as (1.60±0.13 mg.GAE/g) and flavonoids as (1.302±0.4 mg.GAE/g). MEPH GC-MS analysis revealed 20 compounds, including n-hexadeconic acid (Rt-27.385; peak area 41.88%) and 9, 12, Octadecadienoic acid (Z, Z) (Rt-29.879; peak area-19.49%). ABTS and hydroxyl radical scavenging assays showed increased activity based on MEPH concentration. Among the three mosquito larvae tested, only Culex quinquefasciatus proved highly sensitive (100 % mortality), with LC50 and LC90 values of 2.476 and 13.207 ppm. Finally, P. hornemannii may also be considered for application as a biocontrol agent and a nutraceutical in the future.

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In vitro antioxidant study of polyphenol from red seaweeds dichotomously branched gracilaria Gracilaria edulis and robust sea moss Hypnea valentiae

Abstract: Graphical abstract

Cited by 38 publications

References 38 publications

Sargassum filipendula, a Source of Bioactive Compounds with Antioxidant and Matrix Metalloproteinases Inhibition Activities In Vitro with Potential Dermocosmetic Application

Sargassum filipendula, a Source of Bioactive Compounds with Antioxidant and Matrix Metalloproteinases Inhibition Activities In Vitro with Potential Dermocosmetic Application

An Overview on Antimicrobial Potential of Edible Terrestrial Plants and Marine Macroalgae Rhodophyta and Chlorophyta Extracts

Bioactive compounds of Marine Red algae Portieria hornemannii and its bio control effects against Culex quinquefasciatus Dengue vectors

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