In vitro Antiplasmodial and Antibacterial Activities of Canthium multiflorum Schum and Thonn (Rubiacea) Extracts

Akomo, E. F. O.; Zongo, Cheikna; Karou, SD; Obame, Louis Clément; Savadogo, Aly; Attéké, Christiane; Traoré, Alfred S.

doi:10.3923/pjbs.2009.919.923

Cited by 21 publications

(6 citation statements)

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“…[3] The massive use of plants is encouraged by their efficiency, their availability, and the low cost of herbal concoctions. [45] Although many plants have been screened with success for several biological activities,[6–9] some plants have proven very toxic. [1011] Recently, our team identified some critical points in the plant processing and several risks related to the ingestion of contaminated herbal concoctions.…”

Section: Introductionmentioning

confidence: 99%

Medicinal plants use in central Togo (Africa) with an emphasis on the timing

Tchacondo¹,

Karou²,

Agban³

et al. 2012

Phcog Res

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Background:Plant-based remedies continue to play a key role in the health care of people in Togo; however, there is a lack of published data in medicinal plants and medical practices of the people in the country.Objective:This study was aimed at documenting the plant utilization in the Tem folk medicine in the central region of Togo.Materials and Methods:An ethnobotanical survey was conducted with traditional healers in the central region of Togo using a semi-structured questionnaire.Results:This study demonstrated that local specialists in the central region of Togo tend to agree with each other in terms of the plants used to treat diabetes (ICF = 0.38), infertility, and abdominal pains (ICF = 0.33), but cite a much more diverse groups of plants to treat problems related to arterial hypertension, sickle cell disease, and abscess. They use 144 herbal concoctions made of 72 plants, distributed among 36 botanical families. The Euphorbiaceae family with eight species was best represented in terms of the number of species. The species with the highest use value were Khaya senegalensis (Desr.) A. Juss. (Meliaceae) (UV = 0.36), Anthocleista djalonensis A. Chev. (Gentianaceae) (UV = 0.27), Trichilia emetica Vahl (Meliaceae) (UV = 0.25), and Sarcocephalus latifolius (Sm.) E. A. Bruce (Rubiaceae) (UV = 0.21). They also rely on the timing in the plant processing and the administration of herbal remedies.Conclusion:All these findings are based on empirical observations; laboratory screenings are needed to check the effectiveness of these plants.

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Section: Introductionmentioning

confidence: 99%

Medicinal plants use in central Togo (Africa) with an emphasis on the timing

Tchacondo¹,

Karou²,

Agban³

et al. 2012

Phcog Res

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“…However, theses studies are focussed on plant extracts prepared by scientists after collecting plant materials them self. The extractions are made with organic solvents such as chloroform, methanol, or ethanol; sometimes they make decoctions in accordance with traditional practices [6–9]. Very few works have been conducted on vegetable drugs directly provided by TH, since the manufacturing of labelled and packaged herbal concoctions with claims to cure diseases is still new in Africa.…”

Section: Introductionmentioning

confidence: 99%

Assessing Market-Sold Remedies in Lomé (Togo) for Hygienic Quality

Souza

Améyapoh

Karou

et al. 2011

Biotechnology Research International

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Traditional concoctions sold in marketplaces are always assumed to be safe and efficient; however, they can be potentially toxic because of poor hygienic practices in plant processing or storage. The present study aimed to assess for the microbial quality of market-sold vegetable drugs in Lomé. Thus, a total of 209 plant remedies were collected in marketplaces and analysed for the presence of total aerobic bacteria, total coliforms, thermotolerant coliforms, Staphylococcus aureus, sulphite reducing bacteria, and yeast and moulds according to the French Association of Normalisation (AFNOR) guidelines. The results revealed that all formulations were contaminated by several microorganisms, excepted alcohol-based mixtures. According to AFNOR limits nonconform drugs were according to total aerobic bacteria (86.96% powders, 81.82% capsules, 66.67% tisanes, and 42.11% decoctions); to total coliforms (9.10% capsules, 8.70% powders and 1.75% decoction); to yeasts and moulds (77.78% ointments, 40% calcined powders, 36.36% capsules, and 23.91% powders). The microbiological analysis revealed that the majority of contaminating bacteria were gram positive catalase positive and oxidase positive bacilli. Quality control studies on market-sold remedies are currently needed to evaluate the microbial risk in consuming these products and they may allow the standardisation of plant processing and storage.

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“…This test is performed using sterile 96-well microplates according to the protocol described by AKOMO et al (2009). A series of twofold dilutions from 200 mg/ml to 0.39 mg/ml was prepared.…”

Section: Determination Of the Minimum Inhibitory Concentration (Mic)mentioning

confidence: 99%

Chemical composition, antioxidant and antibacterial activity of Adiantum capillus-veneris L. extract from Algeria

Boukada¹,

Sitayeb²,

Khadem³

et al. 2022

Kragujevac J Science

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The present study evaluates the antioxidant and antibacterial activities as well as the chemical composition of the aerial part of Adiantum capillus-veneris L., which are endemic to the flora of Algeria. The total phenolic amount of the hydromethanolic extract, as measured by the Folin-Ciocalteu reagent procedure, was found to be about 23.44 ± 0.14 mg GAE/g DW, while the flavonoid content value was 4.66 ± 0.01 mg CE/g DW, as measured by aluminum chloride colorimetric method. The antioxidant power of the extract was analyzed using the DPPH method. DPPH radicals were scavenged with an IC50 value of 65.85 µg/mL. The antibacterial activity of hydromethanolic extract against five bacterial strains of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 25853), Staphylococcus aureus (ATCC 25923), Streptococcus pneumoniae and Bacillus cereus (ATCC 10876) were carried out using the disc diffusion test and the microdilution method. Streptococcus pneumoniae is the most sensitive bacterium with inhibition zone of 9.0 ± 1.1 cm and MIC=10 mg/mL. Based on HPLC analysis, we find that quercetin 3-O-glucoside was the most abundant compound in the plant extract. This study demonstrates that Adiantum capillus-veneris could be a potential natural source of antibacterial and antioxidant compounds.

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In vitro Antiplasmodial and Antibacterial Activities of Canthium multiflorum Schum and Thonn (Rubiacea) Extracts

Cited by 21 publications

References 0 publications

Medicinal plants use in central Togo (Africa) with an emphasis on the timing

Medicinal plants use in central Togo (Africa) with an emphasis on the timing

Assessing Market-Sold Remedies in Lomé (Togo) for Hygienic Quality

Chemical composition, antioxidant and antibacterial activity of Adiantum capillus-veneris L. extract from Algeria

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