In vitro release kinetics of nisin as affected by Tween 20 and glycerol co-encapsulated in spray-dried zein capsules

Xiao, Dan; Zhong, Qixin

doi:10.1016/j.jfoodeng.2011.04.009

Cited by 21 publications

(9 citation statements)

References 43 publications

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“…Consequently, a larger amount of wet particles can be accumulated on the cyclone wall during spray dying to cause a significantly ( P < 0.05) lower mass yield. Samples with a lower mass yield also resulted in a significantly ( P < 0.05) lower EE, as reported previously . In spray-dried microcapsules, the LC of CAPE was significantly ( P < 0.05) improved at a higher level of CAPE in the feed, with the highest LC of 10.1% in the sample D. The obtained LC is higher than the 0.70% LC when CAPE was loaded in sucrose fatty acid ester nanoparticles .…”

Section: Resultssupporting

confidence: 81%

Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced In Vitro Bioaccessibility and Bioactivity against Colon Cancer Cells

Wang

Leible

Lin

et al. 2020

J. Agric. Food Chem.

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Caffeic acid phenethyl ester (CAPE) has various biological activities but low water solubility and poor bioavailability. In this study, CAPE was encapsulated in skim milk powder (SMP) by spray drying warm aqueous ethanol solutions with different mass ratios of SMP and CAPE. The loading capacity and encapsulation efficiency were up to 10.1 and 41.7%, respectively. Differential scanning calorimetry and X-ray diffraction results confirmed the loss of crystallinity of CAPE after encapsulation. Fourier-transform infrared and fluorescence spectroscopy results indicated the hydrophobic binding between CAPE and caseins. Scanning electron microscopy and static light scattering results showed spherical capsules with an average diameter of around 26 μm. The CAPE loaded in SMP microcapsules showed significantly improved in vitro bioaccessibility and antiproliferation activity against human colon cancer cells compared to free CAPE. The simple, scalable, and low-cost approach in the present study may be significant for industrial encapsulation of CAPE and other lipophilic bioactive compounds.

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Section: Resultssupporting

confidence: 81%

Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced In Vitro Bioaccessibility and Bioactivity against Colon Cancer Cells

Wang

Leible

Lin

et al. 2020

J. Agric. Food Chem.

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“…Zein microparticles were also utilized as carrier of antimicrobials drugs to improve the long-term effectiveness of antimicrobials in foods and to prevent the direct contact of the drug with the food. Zein microcapsules were obtained from spray-drying at different temperatures, and the in vitro release kinetics of nisin was evaluated [ 109 , 110 ]. Nisin is a well-known bacteriocin with 34 amino acids and a molecular weight of 3510 Da.…”

Section: Biomedical Applications Of Zein-based Materialsmentioning

confidence: 99%

“…Numerous studies reported that the antimicrobial activity of nisin is reduced when it is applied in foods, possibly due to binding with food matrix components, which makes the antimicrobial unavailable to inactivate microorganisms. Nisin interacts with zein, mainly through H-bond forces, and whether the release of such drug is favored in a certain condition, the release profiles can be used as guidelines to identify the applicability of a particular nisin delivery system in a given food product [ 109 , 110 ].…”

Section: Biomedical Applications Of Zein-based Materialsmentioning

confidence: 99%

Recent Advances in Food-Packing, Pharmaceutical and Biomedical Applications of Zein and Zein-Based Materials

Corradini

Curti

Meniqueti

et al. 2014

IJMS

246

138

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Zein is a biodegradable and biocompatible material extracted from renewable resources; it comprises almost 80% of the whole protein content in corn. This review highlights and describes some zein and zein-based materials, focusing on biomedical applications. It was demonstrated in this review that the biodegradation and biocompatibility of zein are key parameters for its uses in the food-packing, biomedical and pharmaceutical fields. Furthermore, it was pointed out that the presence of hydrophilic-hydrophobic groups in zein chains is a very important aspect for obtaining material with different hydrophobicities by mixing with other moieties (polymeric or not), but also for obtaining derivatives with different properties. The physical and chemical characteristics and special structure (at the molecular, nano and micro scales) make zein molecules inherently superior to many other polymers from natural sources and synthetic ones. The film-forming property of zein and zein-based materials is important for several applications. The good electrospinnability of zein is important for producing zein and zein-based nanofibers for applications in tissue engineering and drug delivery. The use of zein’s hydrolysate peptides for reducing blood pressure is another important issue related to the application of derivatives of zein in the biomedical field. It is pointed out that the biodegradability and biocompatibility of zein and other inherent properties associated with zein’s structure allow a myriad of applications of such materials with great potential in the near future.

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“…The sample injection volume was 10µL and the mobile phase withequal volumes of acetonitrile and water acidified with 0.1%trifluoroacetic acidwas run at 1.0mL/min. The cumulatively released LAE was calculated using the following equation (Xiao & Zhong, 2011):…”

Section: Release Kinetics Of Laementioning

confidence: 99%

Nanoemulsions of thymol and eugenol co-emulsified by lauric arginate and lecithin

Davidson

Zhong

2016

Food Chemistry

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Lauric arginate (LAE) is a cationic surfactant with excellent antimicrobial activities. To incorporate essential oil components (EOCs) in aqueous systems, properties of EOC nanoemulsions prepared with a LAE and lecithin mixture were studied. The LAE-lecithin mixture resulted in stable translucent nanoemulsions of thymol and eugenol with spherical droplets smaller than 100nm, contrasting with the turbid emulsions prepared with individual emulsifiers. Zeta-potential data suggested the formation of LAE-lecithin complexes probably through hydrophobic interaction. Negligible difference was observed for antimicrobial activities of nanoemulsions and LAE in tryptic soy broth. In 2% reduced fat milk, nanoemulsions showed similar antilisterial activities compared to free LAE in inhibiting Listeria monocytogenes, but was less effective against Escherichia coli O157:H7 than free LAE, which was correlated with the availability of LAE as observed in release kinetics. Therefore, mixing LAE with lecithin improved the physical properties of EOC nanoemulsions but did not improve antimicrobial activities, especially against Gram-negative bacteria.

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In vitro release kinetics of nisin as affected by Tween 20 and glycerol co-encapsulated in spray-dried zein capsules

Cited by 21 publications

References 43 publications

Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced In Vitro Bioaccessibility and Bioactivity against Colon Cancer Cells

Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced In Vitro Bioaccessibility and Bioactivity against Colon Cancer Cells

Recent Advances in Food-Packing, Pharmaceutical and Biomedical Applications of Zein and Zein-Based Materials

Nanoemulsions of thymol and eugenol co-emulsified by lauric arginate and lecithin

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