Inappropriate Medication in a National Sample of US Elderly Patients Receiving Home Health Care

Bao, Yuhua; Shao, Huibo; Bishop, Tara F.; Schackman, Bruce R.; Bruce, Martha L.

doi:10.1007/s11606-011-1905-4

Cited by 74 publications

(78 citation statements)

References 15 publications

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“…Quanto aos fatores de risco relacionados ao uso de MPI, verificou-se que a polifarmácia e a depressão apresentaram significância estatística quanto a essa associação, corroborando com vários outros autores 9,19,34,35 . Como afirmam Bao e colaboradores 35 , não é de surpreender que a polifarmácia foi um fator fortemente associado ao uso de MPI, visto que pacientes com múltiplos medicamentos em uso tem mais chances de receber uma prescrição inadequada e estão mais propensos a ter múltiplas comorbidades, hospitalizações e consultas com médicos de várias especialidades.…”

Section: Discussionunclassified

“…Como afirmam Bao e colaboradores 35 , não é de surpreender que a polifarmácia foi um fator fortemente associado ao uso de MPI, visto que pacientes com múltiplos medicamentos em uso tem mais chances de receber uma prescrição inadequada e estão mais propensos a ter múltiplas comorbidades, hospitalizações e consultas com médicos de várias especialidades.…”

Section: Discussionunclassified

See 1 more Smart Citation

Perfil da farmacoterapia utilizada por idosos institucionalizados

Garbín¹,

Lima²,

Editorial³

et al. 2017

Arch Health Invest

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ResumoIntrodução: O desenvolvimento de patologias crônicas aumenta com o avançar da idade, bem como a quantidade de medicamentos administrados, desafiando o Sistema Único de Saúde quanto a polifarmácia e a farmacovigilância. Objetivos: Este estudo objetivou verificar o perfil da farmacoterapia utilizada por idosos institucionalizados, através da identificação dos medicamentos mais usados, da detecção da ocorrência da polifarmácia e do uso de medicamentos inapropriados para idosos. Material e Método: Os dados foram obtidos através de consulta aos prontuários médicos dos idosos e entrevistas semi-estruturadas às enfermeiras responsáveis de seis Instituições de Longa Permanência para Idosos de quatro municípios do estado de São Paulo. A polifarmácia foi definida através do uso concomitante de cinco ou mais medicamentos diários, sendo que os medicamentos potencialmente inapropriados para idosos foram identificados através dos critérios de Beers. Também foi verificado os fatores associados ao uso de MPI, por meio de análise multivariada. Resultados: Participaram do estudo 261 idosos com idade ≥ 60 anos, sendo que 73,9% foram acometidos pela polifarmácia. Foram prescritos 1452 medicamentos, sendo a maioria (36%) com ação sobre o Sistema Nervoso Central. 50,6% consumiam pelo menos um MPI diariamente, sendo o diazepam (8,4%) e a fluoxetina (7,7%) os mais utilizados. Conclusão: Desta forma, a polifarmácia se faz presente entre a maioria dos idosos, havendo uma prevalência de antipsicóticos e antidepressivos. Quanto ao uso de medicamentos potencialmente inapropriados verificou-se uma alta prevalência, sendo a polifarmácia e a depressão os fatores associados a sua utilização. Descritores: Uso Indevido de Medicamentos sob Prescrição; Idoso; Prescrição Inadequada. AbstractIntroduction: The development of chronic pathologies increases with age, as well as the quantity of drugs administered, challenging the Brazilian public health system regarding polypharmacy and pharmacovigilance. Objectives: This study aimed to verify the profile of pharmacotherapy used by institutionalized elderly, through the identification of the most used drugs, the detection of the occurrence of polypharmacy and the use of inappropriate drugs for elderly. Material and Method: The datas were obtained by consulting the medical records of elderly and applying semi-structured interviews with the responsible nurses of six long-stay institutions for elderly in four cities of São Paulo State, Brazil. Polypharmacy was defined as the concomitant use of five or more daily medications; while potentially inappropriate medications for elderly were identified using the Beers criteria. The factors associated with the use of potentially inappropriate medications were performed by multivariate analysis. Results: The study included 261 elderly aged ≥ 60 years old, being 73,9% affected by polypharmacy. 1452 medications were prescribed, where most of them (36%) act on the central nervous system. 50,6% of the patients consumed at least one potentially inappropriate medicat...

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Section: Discussionunclassified

Perfil da farmacoterapia utilizada por idosos institucionalizados

Garbín¹,

Lima²,

Editorial³

et al. 2017

Arch Health Invest

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“…At the same time, the elderly may appear the phenomenon of memory loss, attention deficit and drug misusage caused by complex medicine species dosage [5].…”

Section: The Individual Characteristics Of the Patients With Hypertenmentioning

confidence: 99%

Medication Safety Management Among Elder with Hypertensive in Community

Wang¹,

Lin²,

Ling³

2017

dtem

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Abstract. This paper reviews the research on the safety management of elderly patients with hypertension in the community in China and abroad. The research involves the concept of elderly hypertension and medication safety, the characteristics of patients with elderly hypertension in the community and some problems with the safety management of them in the community. Based on the above-mentioned research results, this paper draws a conclusion that community hypertensive patients must implement effective drug safety management measures and briefly puts forward some suggestions.

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“…STOPP criteria identified a significantly higher proportion of patients requiring hospitalization due to potentially inappropriate medication related adverse events than Beers' criteria. Inappropriate medications in elderly adults can lead to confusion, falls, cognitive impairment, poor health status, and mortality [34][35][36][37][38] . Adverse Drug Reactions: Adverse drug reactions (ADRs) may be defined as any response that is noxious and unintended and that occurs at doses normally used in man for diagnosis, prophylaxis or therapy, and excluding a failure to accomplish the intended purpose 39 .…”

Section: Inappropriate Drug Prescriptionmentioning

confidence: 99%

Polypharmacy in the Elderly: the Need for Concern and Strategies for its Control

Shola¹,

Adegboye²

2015

ijSciences

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Abstract:In the last three decades, problems related to aging, multi-morbidity, and polypharmacy have become a prominent issue in global healthcare. In this study, Polypharmacy is defined as a concomitant use of five or more drugs simultaneously and/or the administration of more medications than are clinically indicated, representing unnecessary drug use. The purpose of this study was to describe and quantify the magnitude of polypharmacy, analyze the factors associated with this practice among elderly and suggest control measures for its reduction. Other objectives include creating awareness about the risks of multiple drug use in ageing population and propose practical recommendations/interventions regarding rational drug use for elderly age groups. Materials for this study were obtained from a search of the MEDLINE database and International Pharmaceutical Abstracts to identify articles in people aged 60 years and above. A combination of the search terms like polypharmacy, multiple medications, polymedicine, elderly, geriatric, and aged were used. This study found out that polypharmacy is a common problem and a known risk factor for important morbidity and mortality in the elderly. Many medications are associated with negative health outcomes, but more research is needed to delineate the consequences associated with unnecessary drug use in elderly patients. Health care professionals should be aware of the risks associated with polypharmacy and fully evaluate all medications at each patient visit in order to prevent polypharmacy from occurring.

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Inappropriate Medication in a National Sample of US Elderly Patients Receiving Home Health Care

Cited by 74 publications

References 15 publications

Perfil da farmacoterapia utilizada por idosos institucionalizados

Perfil da farmacoterapia utilizada por idosos institucionalizados

Medication Safety Management Among Elder with Hypertensive in Community

Polypharmacy in the Elderly: the Need for Concern and Strategies for its Control

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