Incidence and excess mortality of hip fractures in a predominantly Caucasian population in the South of Brazil

Silva, Dalisbor Marcelo Weber; Lazaretti‐Castro, Marise; Zerbini, Cristiano Augusto de Freitas; Szejnfeld, Vera Lúcia; Eis, Sérgio Ragi; Borba, Victória Zeghbi Cochenski

doi:10.1007/s11657-019-0597-y

Cited by 14 publications

(25 citation statements)

References 38 publications

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“…The incidence rates were predominantly higher in southernmost than in northernmost regions of the country [41]. In agreement with these findings, the frequency of hip fractures observed in the SPAH population (421.2/100,000 pyr in women and 89.9/100,000 pyr in men from São Paulo, a city located in southeast of the country) was close to those reported in cities in the south/southeast of Brazil [18,19,27]. For comparison, Table 4 demonstrates annual incidence rates in Brazilian individuals aged over 60 years after age standardization to the United Nation (UN) data for population demography for the year 2010.…”

Section: Discussionsupporting

confidence: 85%

“…The SPAH is a longitudinal population-based study with several strengths, including a high participation rate and a homogeneous and well-characterized community-dwelling sample which is likely representative of the Brazilian elderly population [22]. Unlike studies using hospital discharge surveys [4,6,[17][18][19]27] whose results may be hindered by underreporting of the fracture diagnosis or misclassification problems in relation to the International Classification of Diseases (ICD-10) codes, the prospective design of our study reduced the possibility of false-positive or false-negative diagnosis. Moreover, fractures were confirmed by radiograph to ensure complete ascertainment.…”

Section: Discussionmentioning

confidence: 99%

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Incidence and risk factors for osteoporotic non-vertebral fracture in low-income community-dwelling elderly: a population-based prospective cohort study in Brazil. The São Paulo Ageing and Health (SPAH) study

et al. 2020

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We ascertained the incidence of non-vertebral fracture in a low-income Brazilian elderly cohort. To the best of our knowledge, this is the first population-based study to demonstrate the frequency of non-vertebral fracture in elderly Latin Americans. Age, prior fracture, and bone mineral density (BMD) at hip were predictors of fracture. Introduction No data on incidence of osteoporotic non-vertebral fracture have been reported in low-income countries where the population's aging has been faster. Even in developed countries, currently available prospective data on major fracture rates beyond hip are scarce. The aim of this study is to describe the incidence and risk factors for non-vertebral fracture in a longitudinal prospective Brazilian population-based elderly cohort. Methods Seven hundred seven older adults (449 women, 258 men) were evaluated at baseline and after a mean follow-up of 4.3 ± 0.8 years. Clinical questionnaire, bone mineral density (BMD), and laboratory tests were performed at baseline. New nonvertebral fracture (hip, proximal humerus, rib, forearm) was determined during the follow-up. Multivariate Poisson regression models were used to identify independent predictors of fracture.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Incidence and risk factors for osteoporotic non-vertebral fracture in low-income community-dwelling elderly: a population-based prospective cohort study in Brazil. The São Paulo Ageing and Health (SPAH) study

et al. 2020

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“…2 Mortality at 1 year after hip fracture is reported to be between 15% and 32%. 3 Several factors influence mortality at one-year, including socioeconomic status and the wait time for surgery. 4 Ensuring access to the resolution of this pathology reduces health costs, increases survival, and improves the life quality of the patients.…”

Section: Introductionmentioning

confidence: 99%

Survival analysis after hip fracture: higher mortality than the general population and delayed surgery increases the risk at any time

et al. 2020

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Purpose: To estimate survival curves in patients with hip fracture according to gender, age, type of fracture, and waiting time for surgery and to compare them with the life expectancy of the general population. The study hypothesis is that survival after hip fractures is significantly lower than in the general population, especially in cases that underwent delayed surgery, regardless of age and gender. Methods: A survival analysis study was designed and approved by our institutional ethics review board. All patients who were coded with a diagnosis of hip fracture from 2002 to 2018 were included in the study. A total of 1176 patients were included, and the median age was 81 years (18–105 years). Kaplan-Meier curves and log-rank tests were performed to compare survival curves between those who underwent surgery on time and those with surgical delays. An exponential multivariate regression model was estimated, and a hazard ratio (HR) was reported for age, gender, and wait time for surgery. A significance of 5% was used, and a confidence interval level of 95% was reported. Results: The Kaplan-Meier curves for delayed surgery (log-rank, p = 0.00) and the age group (log-rank, p = 0.00) were significantly different. Exponential regression estimated an HR 1.05 (1.05–1.07) for age, HR 1.80 (1.51–2.13) for men, and HR 1.93 (1.61–2.31) for each day of wait for surgery. Conclusions: The 2 significant findings of this study are that hip fracture patients over 40 years old have a higher risk of dying at any time compared to the general population and that the waiting time for surgery (a modifiable factor) decreases survival rates at any time.

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“…Researchers in southern Brazil identified a mortality rate above 25% after 12 months of a hip fracture and that this rate is 4,3 times the expected mortality for individuals over 50 years of age [7]. These fractures compromise the independence of individuals who survive them, with more than 50% of them becoming dependent for daily activities and many of them needing institutionalization [3].…”

Section: Introductionmentioning

confidence: 99%

Analysis of risk factors for osteopenia and osteoporosis among adults and elderly in primary health care

Sgarbi¹,

Lopes²,

Alvarenga³

2020

Int J Innov Educ Res

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Objective: To analyze the distribution of risk factors for osteopenia and osteoporosis among adults and elderly in primary care. Method: sectional study of quantitative approach. Random sample extracted from registered adults and elderly from the five Family Health Strategy units belonging to an Expanded Family Health and Primary Care Center in Dourados, MS. Data collected between March and December 2015. The sample consisted of 44 adults and 103 elderly, of which only 109 performed all examinations. Body mass index, bone densitometry, serum calcium, 25 serum hydroxyvitamin D and a structured questionnaire were used. Results: The factors that were significantly associated with the risk of osteopenia and osteoporosis (p <0,05) were female gender, alcohol consumption and normal body mass index. Conclusion: the identification of these risk factors made it possible to trace their distribution profile, which will be of great value for carrying out health promotion actions and prevention of these diseases in Primary Health Care.

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Incidence and excess mortality of hip fractures in a predominantly Caucasian population in the South of Brazil

Cited by 14 publications

References 38 publications

Incidence and risk factors for osteoporotic non-vertebral fracture in low-income community-dwelling elderly: a population-based prospective cohort study in Brazil. The São Paulo Ageing and Health (SPAH) study

Incidence and risk factors for osteoporotic non-vertebral fracture in low-income community-dwelling elderly: a population-based prospective cohort study in Brazil. The São Paulo Ageing and Health (SPAH) study

Survival analysis after hip fracture: higher mortality than the general population and delayed surgery increases the risk at any time

Analysis of risk factors for osteopenia and osteoporosis among adults and elderly in primary health care

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