Incidence, Risk Factors and Treatment Outcomes of Retinopathy of Prematurity in the Southeastern Anatolian Region Province of Şanlıurfa in Turkey

Abstract

(sırasıyla, p<0,001, p<0,001, p<0,001, p<0,001). S So on nu uç ç: : İlimizde, genel PR görülme sık-lığının (%30) Türkiye ortalamasıyla benzer oranlarda görülmesine rağmen agresif seyirli arka PR (%3) ve şiddetli PR (%12,6) görülme sıklığının yüksek olduğu saptandı. Sunulan sağlık hizmetleri politikasının bir parçası olarak Şanlıurfa'da, PR hastalığını görmeyi tehdit edici seviyelere ulaşma-dan önce saptayabilmek için etkili ve uygun bir tarama programı oluşturulmalıdır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Prematüre retinopatisi; insidans; risk faktörleri A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To determine the current incidence and risk factors of retinopathy of prematurity (ROP) and to evaluate treatment choices of ROP. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Two hundred thirty four premature infants, whose the mean birth week was 30.6±2.3 weeks, who had been screened for ROP between May 2014 and June 2015 were enrolled this retrospective study. Infants with ROP were classified according to the gestational age and birth weight. Risk factors were analyzed in infants with ROP. Infants with in need of treatment have been treated, based on the severity of ROP, via either laser photocoagulation (LP) or intravitreal (IV) anti-VEGF injection or LP combined with IV anti-VEGF injection. R Re es su ul lt ts s: : Among the 234 infants, the mean gestational age (GA), mean birth weight (BW), mean follow-up period were 30.6±2.3 weeks, 1573±430 gram and 14.5±4 weeks respectively. Overall, the incidence at any stage of ROP was 30% and severe (Type 1) ROP was 12.6%. Seven of all patients diagnosed with Type 1 ROP had aggressive posterior ROP. The incidences of ROP in babies with gestational age (GA) ≥34 weeks or birth weight (BW) ≥2000 gram were 24% and 18% respectively. Among all risk factors contributed to development of ROP low GA, low BW, septicemia and respiratory distress syndrome were significantly associated with ROP (p<0.001, p<0.001, p<0.001, p<0.001 respectively). C Co on nc cl lu us si io on n: : Although the overall incidence of ROP (30 %) seems to be similar to the average of Turkey, incidence of aggressive post ROP (3%) and severe ROP (12.6 %) is much higher. As a part of general health polices, an effective and compatible screening programs for detecting ROP before reaching sight-threatening levels should be established for Şanlıurfa.

Retinopathy of prematurity among syrian refugees: Incidence and severity

“…Özcan et al . [14] reported that the incidence of severe ROP was higher (18%) in neonates with a BW between 1250 and 1500 g than those of the current study. Bas et al .…”

“…In a study conducted in the same region as the current study, Özcan et al . [14] reported the overall incidence of any stage of ROP as30% and severe ROP as 12%. In the current study, the overall incidence of ROP among Syrian refugees was similar, whereas the incidence of severe ROP was nearly seven times higher than that of infants of Turkish-origin.…”

“…[15]Özcan et al . [14] reported the frequencies of ROP and severe ROP in preterm infants with the same ranges of GA to be nearly higher than those of Syrian refugees. In Turkey, the rates of ROP alter among the regions according to the neonatal care quality, despite the fact that the worst data of the incidence of ROP have been reported in the South-Eastern Anatolian region where many refugees are living and many camps have been established.…”