The purpose of this study is to evaluate whether the presence of any stage retinopathy of prematurity (ROP) alters central retinal artery (CRA) and ophthalmic artery (OA) blood flow parameters in premature infants. The patients were divided into two groups according to the development of ROP; those who have ROP were defined as group I, those without ROP were defined as group II. Ninety eyes of 45 patients in group I and 40 eyes of 20 patients in group II were investigated. The blood flows in the CRA and OA were measured using ultrasound color doppler imaging (CDI) that allows to evaluate the peak systolic velocity (PSV), end diastolic velocity (EDV), and resistivity index (RI). The results were compared between two groups of subjects. There were no significant differences in the PSV, EDV, and RI of CRA between two groups (P = 0.09, P = 0.20 and P = 0.63, respectively). The mean PSV value of OA in group I was found to be significantly higher than the one in group II (P < 0.05), but there were no significant differences in the mean EDV and RI values of OA between two groups (P = 0.40, P = 0.17 respectively). The subgroup analysis revealed that the ocular blood dynamics were not found to be significant between eyes with stage I ROP and eyes with stage II ROP (P > 0.05), whereas the difference in the mean PSV values of OA were found to be significant among the eyes with stage 1 ROP, eyes with stage 2 ROP, and eyes without ROP (P = 0.03). This study demonstrated significant alterations in systolic flow velocities in the OA predicted by CDI in infants with ROP.
(sırasıyla, p<0,001, p<0,001, p<0,001, p<0,001). S So on nu uç ç: : İlimizde, genel PR görülme sık-lığının (%30) Türkiye ortalamasıyla benzer oranlarda görülmesine rağmen agresif seyirli arka PR (%3) ve şiddetli PR (%12,6) görülme sıklığının yüksek olduğu saptandı. Sunulan sağlık hizmetleri politikasının bir parçası olarak Şanlıurfa'da, PR hastalığını görmeyi tehdit edici seviyelere ulaşma-dan önce saptayabilmek için etkili ve uygun bir tarama programı oluşturulmalıdır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Prematüre retinopatisi; insidans; risk faktörleri A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To determine the current incidence and risk factors of retinopathy of prematurity (ROP) and to evaluate treatment choices of ROP. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Two hundred thirty four premature infants, whose the mean birth week was 30.6±2.3 weeks, who had been screened for ROP between May 2014 and June 2015 were enrolled this retrospective study. Infants with ROP were classified according to the gestational age and birth weight. Risk factors were analyzed in infants with ROP. Infants with in need of treatment have been treated, based on the severity of ROP, via either laser photocoagulation (LP) or intravitreal (IV) anti-VEGF injection or LP combined with IV anti-VEGF injection. R Re es su ul lt ts s: : Among the 234 infants, the mean gestational age (GA), mean birth weight (BW), mean follow-up period were 30.6±2.3 weeks, 1573±430 gram and 14.5±4 weeks respectively. Overall, the incidence at any stage of ROP was 30% and severe (Type 1) ROP was 12.6%. Seven of all patients diagnosed with Type 1 ROP had aggressive posterior ROP. The incidences of ROP in babies with gestational age (GA) ≥34 weeks or birth weight (BW) ≥2000 gram were 24% and 18% respectively. Among all risk factors contributed to development of ROP low GA, low BW, septicemia and respiratory distress syndrome were significantly associated with ROP (p<0.001, p<0.001, p<0.001, p<0.001 respectively). C Co on nc cl lu us si io on n: : Although the overall incidence of ROP (30 %) seems to be similar to the average of Turkey, incidence of aggressive post ROP (3%) and severe ROP (12.6 %) is much higher. As a part of general health polices, an effective and compatible screening programs for detecting ROP before reaching sight-threatening levels should be established for Şanlıurfa.
Retinopathy of prematurity (ROP) has been a major problematic disorder during childhood. Laser photocoagulation (LPC) has been proven to be effective in most of the ROP cases. Adenoviral conjunctivitis (AVC) is responsible for epidemics among adult and pediatric population. It has also been reported to be a cause of outbreaks in neonatal intensive care units (NICU) several times. We herein demonstrate a case with AVC who underwent LPC for ROP. And we discuss the treatment methodology in such cases.
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