Incidence, Timing, and Follow-Up of Periventricular Leukomalacia

Goetz, Mary C.; Gretebeck, Ronda J.; Oh, Kook Sang; Shaffer, Diane; Hermansen, Marcus C.

doi:10.1055/s-2007-994486

Cited by 23 publications

(15 citation statements)

References 5 publications

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“…As in our study, such critically ill babies clearly deserve repeat scans. Goetz et al, 36 similar to the study of Andre et al 14 and to our study, noted that infants who had initial normal HUS and developed late cystic PVL were of shortest GA and lowest BW. Goetz et al recommended different schedules of HUS screening based on BW.…”

Section: Andre Et Alsupporting

confidence: 91%

“…A number of investigators have suggested more intensive schedules for performing HUS evaluations. 12,[34][35][36] In the report by Pierrat et al 34 infants with extensive PVL (grade III PVL) developed cystic changes within the first 2 to 3 weeks of life; and infants with localized PVL (grade II PVL) were noted to develop cysts only after the first month of life. However, 97% of all their infants with grade II PVL had echodensities on their first screening study, a finding that would have placed those infants into the major abnormality group in our study.…”

Section: Commentsmentioning

confidence: 99%

See 1 more Smart Citation

Serial Head Ultrasound Studies in Preterm Infants: How Many Normal Studies Does One Infant Need to Exclude Significant Abnormalities?

2003

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Section: Andre Et Alsupporting

confidence: 91%

Section: Commentsmentioning

confidence: 99%

Serial Head Ultrasound Studies in Preterm Infants: How Many Normal Studies Does One Infant Need to Exclude Significant Abnormalities?

2003

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“…27,43,44 In one report, 28 cystic PVL and ventriculomegaly were found in 8 (3%) of 256 neonates after previously normal US findings. For infants weighing Ͻ1,000 grams, 3 (50%) of 6 cases of PVL were noted at 36 to 40 weeks' postmenstrual age.…”

Section: Whichmentioning

confidence: 95%

“…25,28,41,43 In these studies, grades 3 and 4 IVH was noted in 11% of infants with BW of Ͻ1,000 grams and in 5% of infants with BW of 1,000 to 1,250 grams; when infants were compared by GA groups, 16% of those with GA of Յ25 weeks and 1% to 2% of infants with GA of Ͼ25 weeks had grades 3 and 4 IVH (see the electronic version of this article for table 5 at www.neurology.org). Likewise, cystic PVL was noted in 5% to 26% of infants weighing Ͻ1,000 grams, compared with 1% to 5% of infants with BW of Ͼ1,000 grams.…”

Section: Whichmentioning

confidence: 99%

Practice parameter: Neuroimaging of the neonate: [RETIRED]

Ment

Bada²,

Barnes³

et al. 2002

Neurology

393

100

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Article abstract-Objective: The authors reviewed available evidence on neonatal neuroimaging strategies for evaluating both very low birth weight preterm infants and encephalopathic term neonates. Imaging for the preterm neonate: Routine screening cranial ultrasonography (US) should be performed on all infants of Ͻ30 weeks' gestation once between 7 and 14 days of age and should be optimally repeated between 36 and 40 weeks' postmenstrual age. This strategy detects lesions such as intraventricular hemorrhage, which influences clinical care, and those such as periventricular leukomalacia and low-pressure ventriculomegaly, which provide information about long-term neurodevelopmental outcome. There is insufficient evidence for routine MRI of all very low birth weight preterm infants with abnormal results of cranial US. Imaging for the term infant: Noncontrast CT should be performed to detect hemorrhagic lesions in the encephalopathic term infant with a history of birth trauma, low hematocrit, or coagulopathy. If CT findings are inconclusive, MRI should be performed between days 2 and 8 to assess the location and extent of injury. The pattern of injury identified with conventional MRI may provide diagnostic and prognostic information for term infants with evidence of encephalopathy. In particular, basal ganglia and thalamic lesions detected by conventional MRI are associated with poor neurodevelopmental outcome. Diffusion-weighted imaging may allow earlier detection of these cerebral injuries. Recommendations: US plays an established role in the management of preterm neonates of Ͻ30 weeks' gestation. US also provides valuable prognostic information when the infant reaches 40 weeks' postmenstrual age. For encephalopathic term infants, early CT should be used to exclude hemorrhage; MRI should be performed later in the first postnatal week to establish the pattern of injury and predict neurologic outcome.

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“…White matter abnormalities, which may manifest as echodensities, ventriculomegaly or cystic changes, may be present at birth but they often appear later (30). Cystic periventricular leukomalacia of antenatal onset is evident by two weeks of age (31).…”

Section: When Should Cranial Ultrasound Examinations Be Performed?mentioning

confidence: 99%

Routine screening cranial ultrasound examinations for the prediction of long term neurodevelopmental outcomes in preterm infants

Sauve¹

2001

Paediatrics &Amp; Child Health

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Routine screening cranial ultrasound examinations for the prediction of long term neurodevelopmental outcomes in preterm infants S ince the late 1970s, cranial ultrasound examinations have been performed on preterm infants to provide information about perinatal brain injury for the prediction of long term outcomes (1). Cranial ultrasound examinations and nonultrasound brain imaging techniques, such as magnetic resonance imaging, have also been used for a variety of clinical indications (2-5). Because of recent developments in the technology and process of performing cranial ultrasound examinations (6), and in the classification and understanding of the predictive value of abnormal findings (7-11), it is timely and important to consider the value and process of determining the need for routine screening cranial ultrasound examinations in neonatal intensive care units (NICUs).

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Incidence, Timing, and Follow-Up of Periventricular Leukomalacia

Cited by 23 publications

References 5 publications

Serial Head Ultrasound Studies in Preterm Infants: How Many Normal Studies Does One Infant Need to Exclude Significant Abnormalities?

Serial Head Ultrasound Studies in Preterm Infants: How Many Normal Studies Does One Infant Need to Exclude Significant Abnormalities?

Practice parameter: Neuroimaging of the neonate: [RETIRED]

Routine screening cranial ultrasound examinations for the prediction of long term neurodevelopmental outcomes in preterm infants

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