Incidental finding of sclerosing angiomatoid nodular transformation of the spleen

Abstract

SANT of the spleen are very rare tumors and should be considered as an important differential diagnosis to other vascular lesions.

Sclerosing Angiomatoid Nodular Transformation of the spleen, focal nodular hyperplasia and hemangioma of the liver: A tale of three lesions

“…It often affects middle age women (mean age at diagnosis: 45 years; male to female ratio: 0.8), despite pediatric cases have also been reported. Up to 14% of SANTs co-exists with abdominal/extra-abdominal tumors, but such an association is likely due to the thorough diagnostic/staging procedures performed in oncologic patients (Table 1) [4,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21].…”

Sclerosing Angiomatoid Nodular Transformation of the Spleen

“…Symptomatic patients most commonly present with abdominal pain, splenomegaly, or a palpable left upper quadrant mass. 2 Sclerosing angiomatoid nodular transformation arises from the red pulp of the spleen and is ''characterized by a single large mass composed of numerous variably sized vascular (angiomatoid) nodules separated by fibrous stroma.'' 3 Several benign and malignant lesions are within the differential diagnosis of SANT radiographically.…”

Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients

“…The correct diagnosis of SANT pre-intervention or preoperatively is a significant problem in clinical practice because in imaging it presents with the same features as a malignancy. Therefore radiology-pathology corroboration is highly recommended [ [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] ]. A multidisciplinary approach should include specialists in radiology, gastrointestinal surgery, pathology and gastrointestinal oncology in order to evaluate the possibility of malignity in SANT patients [ [31] , [32] , [33] , 35 , 36 ].…”

“…A total of 230 SANT patients undergoing laparoscopic, open splenectomy or biopsy between 2004 and April 2020 were reported on in English language literature [ [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] ]. Patient information was only retrieved from English language medical databases with full-texts, using Google Scholar, PubMed, Scopus and Research-gate.…”