Incompatible Results on Matched Cross Test Examination

Abstract

Compatibility testing before blood transfusion is very crucial. This procedure to prevent transfusion reactions due to blood group incompatibility or irregular antibodies. Cross-matching to ensure that the blood safe for the recipient. There are two results in the cross-matching, namely compatible and incompatible. This study aims to determine the inappropriate results of cross-matching at Blood Transfusion Service of the Indonesian Red Cross, Kulon Progo Regency. This study used a quantitative descriptive research design with a retrospective approach. The samples used in this study were 78 incompatible samples in Blood Transfusion Service of the Indonesian Red Cross, Kulon Progo Regency. The sampling technique used was the total population. Methods of data analysis using descriptive analysis. The results show incompatibilities of most compatible cross tests found in minor and auto control (96.1%) with male gender frequency (35.9%) and women (64.1%). The most blood type that has incompatibilities is blood type O (43.3%). The most Diagnosis is anemia (76.9%), and the most components are PRC (88.4%). The most incompatible types are minor and auto control and the most commonly encountered in women, O blood type, anemia, and components of PRC.

Profile of Incompatible Reactions to Packed Red Cell Transfusion in Patients With Chronic Kidney Disease at Sanglah Hospital

“…The high number of CKD patients at Sanglah Denpasar Hospital who experienced incompatible cross-match results reached 37 people (17.63%) in the elderly category. This must be considered when transfusion to cross-match before transfusion to minimize incompatible events that risk fatality (Aljannah and Supadmi, 2021;Raturi et al, 2021).…”

“…If these results are not evaluated, they can harm the patient and result in high fatalities. An effort can be made by cross-matching with repetition to ensure good results before transfusion to the patient (Aljannah and Supadmi, 2021).…”

“…Since the discovery of the ABO blood type by Karl Landsteiner in 1901 and the Rhesus factor (Rh) by Levine in 1939, all blood transfusions taken from known donors of the ABO group and its Rh factor, thus the results of cross-matching are generally appropriate (compatible), transfused to the patient well. Nevertheless, there is an exception process in exceptional cases, for example, Lewis a or Lewis b antibodies in patients whose classes Lewis a and b are antagonistic (Aljannah and Supadmi, 2021).…”