Latar Belakang: Coronavirus Disease 2019 (COVID-19) disebabkan oleh Sars-CoV-2 termasuk jenis virus corona, merupakan penyakit yang menyebabkan gangguan pernapasan akut dengan masa inkubasi rata-rata 5 hingga 14 hari. Pada kasus COVID-19 berat dapat menyebabkan pneumonia, sindrom pernapasan akut, gagal ginjal, dan bahkan kematian. Berbagai upaya telah dilakukan guna mencegah penyebaran infeksi, dengan dikeluarkannya berbagai protokol pencegahan dan penatalaksanaan terhadap pasien terinfeksi salah satunya terkait penggunaan plasma konvalesen sebagai terapi suportif. Penelitian ini bertujuan untuk melihat bagaimana prosedur penggunaan plasma konvalesen untuk terapi suportif pasien Covid-19Metode: Jenis dan rancangan penelitian ini adalah literature review. Data yang digunakan adalah data sekunder berupa artikel atau jurnal dari penelitian terdahulu yang relevan dengan topik penelitian. Staregi pencarian data menggunakan database Google Scholar dan Pubmed. Seleksi studi dilakukan untuk menentukan artikel yang akan direview. Hasil catatan informasi dari artikel yang ditelaah disusun dalam tabel ektrasi data. Hasil literature review dianalisis dengan menggunakan tema sesuai temuan dari artikel.Hasil: Hasil review, dengan terapi plasma konvalesen bagi pasien Covid-19 terdapat perbaikan tanda dan gejala, peningkatan PAO2/FIO2, perbaikan gambaran radiologi, peningkatan titer antibodi IgM dan IgG, pemulihan kondisi secara umum dan kesembuhan hingga pasien boleh pulang dari rumah sakit.Kesimpulan: Terapi plasma konvalesen efektif memperbaiki dan mengobati Covid-19.

The quality test of the PRC components is needed to ensure a consistent processing and storage processes for an optimal healing effect. Hemolysis during blood storage is the most severe manifestation of erythrocyte storage and is an important parameter for assessing the quality of PRC [1], [2]. This study aims to measure the level of PRC hemolysis as an indicator of quality during processing and storage. This is an observational descriptive study using a comparative analytical approach (student t-test). The previous researches on PRC on the bloods collected inside the building revealed that the average increase in hemolysis occurred on the 0th day along with the gradual increase in the next processing even though it was still under the standard of below 0.8% at the end of storage. It was also noted that PRC hemolysis on mobile unit (MU) collection significantly increased on 14th day. The most significant increase in hemolysis occurred at PRC drawing of MU on 7th day from 0.3 to 0.5. Furthermore, the PRC hemolysis of the two groups continued to increase variably until the end of the storage period, particularly on day 35 although it remained below the level of 0.8%. The t-test results show a significant level of (p) 0.001, that is lower than 0.05. Thus, it can be concluded that there is a significant score difference in the PRC hemolysis between the Blood Transfusion Unit blood sampling and mobile unit (MU) blood collection activities.

Antibacterial compounds are compounds that can inhibit bacterial growth. The components contained in the basil leaf extract have the potential to be developed as a source of antibacterial active ingredients. Basil leaves are a plant that has antibacterial potential. This study aims to test the antibacterial activity of the basil leaf extract (Ocimum sanctum L.) with various concentrations of 20%, 40%, 60%, 80%, and 100% against Staphylococcus aureus ATCC 25923. Antibacterial activity test using the well diffusion method. The results showed that basil leaf extract (Ocimum sanctum L.) concentrations of 20%, 40%, 60%, 80%, and 100% could inhibit the growth of Staphylococcus aureus ATCC 25923. The concentration of basil leaf extract was 100% effective as an antibacterial against Staphylococcus aureus bacteria. ATCC 25923 of 12.60 mm.

Blood donation is someone who voluntarily gives blood; then, the feasibility is processed and transfused to patients in need. Blood donors come from voluntary blood donors or substitute donors/families or certain communities. The COVID-19 pandemic is the spread of a coronavirus epidemic that has spread to various continents and countries. This research is a quantitative descriptive study with a time approach used as a retrospective. The number of donations before the pandemic was 18,661, the number of donations during the pandemic was 22,882, and media for disseminating information using the Whatsapp application. The increase in the number of blood donations during the COVID-19 pandemic and the efforts made to keep donors from donating blood during the COVID-19 pandemic.

Compatibility testing before blood transfusion is very crucial. This procedure to prevent transfusion reactions due to blood group incompatibility or irregular antibodies. Cross-matching to ensure that the blood safe for the recipient. There are two results in the cross-matching, namely compatible and incompatible. This study aims to determine the inappropriate results of cross-matching at Blood Transfusion Service of the Indonesian Red Cross, Kulon Progo Regency. This study used a quantitative descriptive research design with a retrospective approach. The samples used in this study were 78 incompatible samples in Blood Transfusion Service of the Indonesian Red Cross, Kulon Progo Regency. The sampling technique used was the total population. Methods of data analysis using descriptive analysis. The results show incompatibilities of most compatible cross tests found in minor and auto control (96.1%) with male gender frequency (35.9%) and women (64.1%). The most blood type that has incompatibilities is blood type O (43.3%). The most Diagnosis is anemia (76.9%), and the most components are PRC (88.4%). The most incompatible types are minor and auto control and the most commonly encountered in women, O blood type, anemia, and components of PRC.