Measurement of Pack Red Cells (PRC) Blood Components During Processing and Storage

Abstract

The quality test of the PRC components is needed to ensure a consistent processing and storage processes for an optimal healing effect. Hemolysis during blood storage is the most severe manifestation of erythrocyte storage and is an important parameter for assessing the quality of PRC [1], [2]. This study aims to measure the level of PRC hemolysis as an indicator of quality during processing and storage. This is an observational descriptive study using a comparative analytical approach (student t-test). The previous researches on PRC on the bloods collected inside the building revealed that the average increase in hemolysis occurred on the 0th day along with the gradual increase in the next processing even though it was still under the standard of below 0.8% at the end of storage. It was also noted that PRC hemolysis on mobile unit (MU) collection significantly increased on 14th day. The most significant increase in hemolysis occurred at PRC drawing of MU on 7th day from 0.3 to 0.5. Furthermore, the PRC hemolysis of the two groups continued to increase variably until the end of the storage period, particularly on day 35 although it remained below the level of 0.8%. The t-test results show a significant level of (p) 0.001, that is lower than 0.05. Thus, it can be concluded that there is a significant score difference in the PRC hemolysis between the Blood Transfusion Unit blood sampling and mobile unit (MU) blood collection activities.

Produksi Komponen Darah Packed-Red Cell (PRC), Liquid Plasma (LP), Thombocytes Concentrates (TC) dan Fresh-Frozen-Plasma (FFP) di UDD PMI Kabupaten Bojonegoro

“…Kerusakan eritrosit dapat terjadi apabila proses pengolahan dan penyimpanan tidak sesuai standart. Kesesuaian penyimpanan PRC pada temperature yang yang teoat dapat menghambat kerusakan PRC, dimana eliminasi kantong PRC yang rusak dapat mengurangi stok PRC pada UDD PMI Bojonegoro (Romana & Supadmi, 2021).…”