Incorporation and release of drug into/from superparamagnetic iron oxide nanoparticles

Maver, Uroš; Bele, Marjan; Makovec, Darko; Čampelj, Stanislav; Jamnik, J.; Gaberšček, Miran

doi:10.1016/j.jmmm.2009.05.054

Cited by 29 publications

(15 citation statements)

References 26 publications

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“…Among them the sol-gel method has been shown to be very useful for preparation of iron oxide nanoparticles dispersed in an amorphous silica matrix. Silica is convenient because of its nontoxic nature, high biocompatibility, prevention of agglomeration, temperature resistance, chemical inertness and adjustable pore diameter [1,2,8,10,21,32,36,37,49,50,[52][53][54]57,61,67,[81][82][83][84].…”

Section: Introductionmentioning

confidence: 99%

Highly crystalline superparamagnetic iron oxide nanoparticles (SPION) in a silica matrix

Tadić

Kusigerski

Marković

et al. 2012

Journal of Alloys and Compounds

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Section: Introductionmentioning

confidence: 99%

Highly crystalline superparamagnetic iron oxide nanoparticles (SPION) in a silica matrix

Tadić

Kusigerski

Marković

et al. 2012

Journal of Alloys and Compounds

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“…Useful diagnostic modalities are MRI with T1 and/or T2 sensitive agents, fluorescein markers, and radionuclides [56,57]. [107][108][109][110] Quantum dots [137][138][139][140][141][142] Nanotubes [128][129][130][131][132][133] Nanomaterials Polymeric mycelia and nanospheres [115][116][117][118] Solid lipid nanoparticles [113,114] Gold nanoparticles [143][144][145][146][147] Mesoporous nanoparticles based on silica [134][135][136] Dendrimers [121][122][123][124][125] Therapy [177][178][179][180][181][182][183] Magnetic activation [98][99][100][101]…”

Section: Methods To Achieve Controlled Drugmentioning

confidence: 99%

“…, sized 10-100 nm, which are responsive to a magnetic field, are used as multimodal drug delivery systems, based on their superparamagnetic properties [98,99]. Materials, used most often, are iron oxide nanoparticles (IONP) [100,101]. They are used in two main forms, namely, magnetite (Fe 3 O 4 ) and its oxidised metabolite, maghemite ( -Fe 2 O 3 ) [102].…”

Section: Magnetic Activation Magnetic Nanoparticles (Mnps)mentioning

confidence: 99%

Skin Cancer and Its Treatment: Novel Treatment Approaches with Emphasis on Nanotechnology

Orthaber

Pristovnik

Skok

et al. 2017

Journal of Nanomaterials

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The life expectancy in the Western world is increasing for a long time, which is the courtesy of a higher life standard, a more thorough hygiene, and, of course, the progress of modern medicine. Nevertheless, one of the illnesses that still proves to be a great challenge regardless of the recent advancements in medicine is cancer. Skin cancer is, according to the World Health Organization, the most common malignancy for the white population. The beginning of the paper offers a brief overview of the latest available information concerning epidemiology, aetiology, diagnostics, and treatment options for skin cancer, whereas the rest of the article deals with modern approaches to skin cancer treatment, highlighting recent development of nanotechnology based treatment approaches. Among these, we focus especially on the newest nanotechnological approaches combined with chemotherapy, a field which specialises in target specificity, drug release control, and real time monitoring with the goal being to diminish unwanted side effects and their severity, achieving a cheaper treatment and a generally more efficient chemotherapy. The field of nanotechnology is a rapidly developing one, judging by already approved clinical studies or by new theranostic agents that combine both the therapeutic and diagnostic modalities.

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“…1(b-d) shows IONPs collected after peptization was stable. This phenomenon occurred because of the Van der Waals, magnetic and electrostatic forces presence between IONPs that led to agglomeration [22]. After peptization with acids, the presence of electrostatic force between IONPs prevents agglomeration of particles.…”

Section: Synthesis Of Iron Oxidementioning

confidence: 99%

Properties of surface functionalized iron oxide nanoparticles (ferrofluid) conjugated antibody for lateral flow immunoassay application

Nor

Razak

Tan³

et al. 2012

Journal of Alloys and Compounds

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Incorporation and release of drug into/from superparamagnetic iron oxide nanoparticles

Cited by 29 publications

References 26 publications

Highly crystalline superparamagnetic iron oxide nanoparticles (SPION) in a silica matrix

Highly crystalline superparamagnetic iron oxide nanoparticles (SPION) in a silica matrix

Skin Cancer and Its Treatment: Novel Treatment Approaches with Emphasis on Nanotechnology

Properties of surface functionalized iron oxide nanoparticles (ferrofluid) conjugated antibody for lateral flow immunoassay application

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