Incorporation of Antimicrobial Macromolecules in Acrylic Denture Base Resins: A Research Composition and Update

Abstract

Contemporary research in acrylic denture base materials focuses on the development of a novel poly(methyl methacrylate) (PMMA) resin with antimicrobial properties. Although PMMA resin has fulfilled all the requirements of an ideal denture base material, its susceptibility to microbial colonization in the oral environment is a formidable concern to clinicians. Many mechanisms including the absence of ionic charge in the methyl methacrylate resins, hydrophobic interactions, electrostatic interactions, and mechanical attachment have been found to contribute to the formation of biofilm. The present article outlines the basic categories of potential antimicrobial polymer (polymeric biocides) formulations (modified PMMA resins) and considers their applicability, biological status, and usage potential over the coming years.

Elemental ion release and cytotoxicity of antimicrobial acrylic resins incorporated with nanomaterial

“…Such an addition may reduce biofilm retention and promote the maintenance of a clean environment. A successful antimicrobial should represent a significant advance in the prevention of pathologies and improve the quality of life of patients with prosthetic devices, representing an advance with great clinical relevance …”

“…A successful antimicrobial should represent a significant advance in the prevention of pathologies and improve the quality of life of patients with prosthetic devices, representing an advance with great clinical relevance. 5,6 Nanotechnology, a science of the understanding and control of matter at the nanometre scale (between 1 and 100 nm), has attracted interest for improving the biological properties of dental materials. 7 Nanoscale materials demonstrate inherent characteristics that confer the ability to penetrate biological membranes such as the cell walls of bacteria, increasing the bactericidal effects.…”

The influence of the post-processing method on knoop hardness of photosensitive resins for 3D SLA printer used in Dentistry

“…5 Despite the material's components of 3DR being similar to AR (Table 1), there are differences regarding the components of 3DR and the photoinitiators and the different degree of material conversion that could lead to different mechanical proprieties. 6,7,8,9…”

Comparison of the Effect of Nystatin and Titanium Dioxide Addition on Candida Colonization in Soft Lining Material

“…Uchimaru et al 24 reported that TiO 2 , which is a stable photocatalyst, combined with a tissue conditioner exhibited antimicrobial activity against Escherichia coli, S. mutans, and S. aureus, and antifungal activity against C. albicans. TiO 2 exhibits strong oxidizing power under UV radiation (from sunlight or an illuminated light source) 36 but no photocatalystic effects at nonradiation, 37,38 which means soft liners with TiO 2 may have no antifungal effect in the oral cavity environment. 38 When dentures are removed, for instance during sleep, the photocatalystic agents can allow for the maintenance of soft liners by radiation alone.…”