Increased Platelet Distribution Width Is Associated With ST-Segment Elevation Myocardial Infarction and Thrombolysis Failure

Çetın, Mustafa; Bakırcı, Eftal Murat; Baysal, Erkan; Taşolar, Hakan; Ballı, Mehmet; Cakici, Musa; Abuş, Sabri; Aktürk, Erdal; Özgül, Sami

doi:10.1177/0003319713520068

Cited by 58 publications

(60 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 Platelet count and platelet parameters such as platelet distribution width are usually measured along with MPV, and significant differences have been observed in thrombosis and cardiovascular events as well as MPV. 13,14 However, no reports concerning these two indices have been found for hypertension. Compared with platelet count and platelet distribution width, MPV seems to be very stable and has more associated discoveries in recent studies.…”

Section: Discussionmentioning

confidence: 99%

Association between mean platelet volume and hypertension incidence

Li¹,

Zhang²,

Zhu³

et al. 2017

Hypertens Res

View full text Add to dashboard Cite

Mean platelet volume (MPV) is increased in various cardiovascular diseases. We sought to determine the prognostic value of MPV for hypertension. We performed a retrospective cohort study. Baseline characteristics were measured in 9168 individuals without hypertension, and the follow-up period was 9 years. Hypertension was confirmed in 2881 participants during the followup period. When the participants were grouped according to MPV quartiles, the hazard ratio of future hypertension gradually increased across the MPV quartiles. The hazard ratios of hypertension for the II, III and IV (high) vs. I (low) quartiles of MPV were 1.13 (95% confidence interval (CI) 1.01-1.25, P = 0.027), 1.25 (95% CI 1.12-1.39, Po0.001) and 1.40 (95% CI 1.26-1.55, Po0.001), respectively. In multivariate Cox regression analysis, MPV predicted hypertension independently of age, sex, platelet count, waist circumference, drinking, systolic blood pressure and creatinine levels. The present study indicated that elevated MPV is associated with increased incidence of hypertension independent of other risk factors, which suggests that platelet activity may play a role in hypertension incidence.

show abstract

Section: Discussionmentioning

confidence: 99%

Association between mean platelet volume and hypertension incidence

Li¹,

Zhang²,

Zhu³

et al. 2017

Hypertens Res

View full text Add to dashboard Cite

show abstract

“…Also it has been studied that PDW is higher in patients with STEMI rather than stable Coronary Artery Disease (CAD). Rather than just association they also influence the success of thrombolysis in STEMI patients [34] There are several studies which analysed the risk of Platelet Distribution Width (PDW) in acute coronary syndrome like ST Elevtion Myocardial Infarction. Varasteh-ravan et al [30] studied the relationship of platelet distribution width in patients with acute STEMI thrombolysed with streptokinase and found that patients with higher platelet distribution width had more risk of thromblysis failure measured by ST segment resolution.…”

Section: Conclusion Ionmentioning

confidence: 99%

Raised Platelets Distribution Width as a Risk Assessment Prognostic Tool For Post Myocardial Infarction Patients

Koolwal¹

2017

JMSCR

View full text Add to dashboard Cite

Objectives & Aims: The evaluation and identify new prognostic markers suggested in recent studies for coronary heart disease ,raised platelets distribution width (PDW) has been found to be associated with poor prognosis after resent myocardial infarction. Evaluate the relationship between raised PDW and mortality morbidity after the initial attack of myocardial infarction (MI). Increased platelets distribution width (PDW) has been associated with adverse outcomes. We studied the association between raised PDW during hospital course with clinical outcomes survival index of patients with after acute myocardial infarction (AMI

show abstract

“…Estimating the risk of reperfusion failure in individual patients before initiation of thrombolytic therapy may be helpful to determine the optimal treatment strategy especially for patients admitted to non-PCI capable hospitals. Previous studies reported that parameters such as red cell distribution width, mean platelet volume, platelet distribution width and C-reactive protein (CRP) on admission may be helpful in predicting failed reperfusion [4][5][6][7]. However, according to available literature, there is currently no scoring system which can be used to predict failed reperfusion in STEMI patients to whom thrombolytic therapy is given.…”

Section: Introductionmentioning

confidence: 99%