Influence of age, gender, and serum triglycerides on heart rate in a cohort of asymptomatic individuals without heart disease

Paula, Rogério Silva de; Antelmi, Ivana; Vincenzi, M; André, Carmen Diva Saldiva de; Artes, Rinaldo; Grupi, César José; Mansur, Alfredo José

doi:10.1016/j.ijcard.2004.11.023

Cited by 8 publications

(5 citation statements)

References 34 publications

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“…None of our patients were newly diagnosed with atrioventricular block or bradyarrhythmia. As RB patients were significantly older than NB patients in our study, the decrease in heart rate variability in the elderly may have played a role [30] . While mean heart rates are not significantly related to age or gender, minimum heart rates are higher and maximum heart rate are lower in the elderly, particularly elderly men [30,31] .…”

Section: Discussionmentioning

confidence: 52%

“…As RB patients were significantly older than NB patients in our study, the decrease in heart rate variability in the elderly may have played a role [30] . While mean heart rates are not significantly related to age or gender, minimum heart rates are higher and maximum heart rate are lower in the elderly, particularly elderly men [30,31] . On the other hand, RB remained significant when adjusting for age in our multiple regression analysis.…”

Section: Discussionmentioning

confidence: 53%

“…Approximately 50% of AP patients have abnormal findings on electrocardiogram which generally resolve upon recovery, with atrioventricular block and bradyarrhythmias in rare cases [28–30] . The relationship between fever and heart rate has not been studied in the context of pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

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Clinical outcomes in acute pancreatitis with relative bradycardia at fever onset

et al. 2021

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While some acute pancreatitis (AP) patents with fever do not exhibit a corresponding increase in heart rate, the clinical significance of this phenomenon has not been studied. We investigated the clinical relevance of relative bradycardia (RB) in febrile AP.A retrospective electronic chart review was conducted on consecutive patients admitted for AP at a tertiary referral center in Japan from January 1, 2010, to May 31, 2018. Presence of RB was determined at the first instance of fever, based on formulas used in previous studies.Fever at or during admission was observed in 115 patients, of which 33% had RB. Fever was observed at presentation in 48% and within 48 hours in 94% of cases. Etiologies were alcoholic in 48% and gallstones in 17% of cases. RB patients were older (median age: 62 vs 51 years, P = .028) but had shorter median postfever lengths of stay (8 vs 12 days, P = .003), lower median Ranson scores (1 vs 2, P < .001), and were less likely to develop delirium (11% vs 38%, P = .002). Nineteen of 21 severe AP cases based on the Ranson score were nonbradycardia (P = .011). RB was also associated with lower white blood cell count, C-reactive protein, and lactate levels. On computed tomography, necrosis (P = .028) and moderate or severe pancreatitis (P = .041) were less frequently observed in patients with RB. There was a significant inverse correlation between RB and the Ranson score (À.305, P = .001). While RB was an independent predictors of postfever length of stay (LOS) in multiple regression analysis when the Ranson score was excluded (P = .010), it ceased to be significant when the Ranson score was included (P = .141).AP patients with RB at fever onset had milder disease and shorter LOS compared to those with higher heart rates at fever onset. RB may be useful as a simple, early predictor of shorter LOS before the Ranson score can be calculated.

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Section: Discussionmentioning

confidence: 52%

Section: Discussionmentioning

confidence: 53%

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Clinical outcomes in acute pancreatitis with relative bradycardia at fever onset

et al. 2021

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“…4 Physiological functioning also changes systematically with age (Taddei et al, 2001). Further, sex (1 = male, 2 = female) is associated with higher triglycerides; specifically, men are more likely to have higher triglycerides levels (Silva de Paula et al, 2005). Social support through the presence of a partner also influences triglycerides (Hemingway & Marmot, 1999), therefore, we control for marital status.…”

Section: Methodsmentioning

confidence: 99%

Under Pressure: The Effect of Antioxidants on Health Consequences Related to Oxidative Stress

Patel

Wolfe

2020

Entrepreneurship Theory and Practice

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We examine the relationships between oxidative stress (i.e., manifestations of physiological stress), antioxidants, potentially negative health outcomes (i.e., triglyceride levels), and self-employment through two studies. Our results indicate that oxidative stress is associated with higher triglyceride levels and, as hypothesized, this relationship is mitigated in the presence of higher levels of antioxidants. Perhaps most interestingly, in both studies, we find that oxidative stress has a stronger positive relationship with triglyceride levels for individuals who are self-employed and have lower antioxidant levels relative to employed individuals. We discuss the implications of these findings on research regarding self-employment, stress, and well-being.

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“…The findings of the study support the hypothesis that maximum heart rate relative to age based on studies with a predominance of male patients may be an overestimate for women and demonstrated an inverse relationship between peak heart rate with increasing age. Previously, we have observed that an inverse relationship of maximum daily heart rate with increasing age was also apparent in individuals with no evidence of heart disease on common everyday living activities evaluated by 24-h ECG monitoring [4].…”

Section: Significancementioning

confidence: 99%

Heart Rate Response and Chronotropic Incompetence in Exercise Stress Testing of Asymptomatic Women

Mansur

Nunes

2010

Womens Health (Lond Engl)

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Evaluation of: Gulati M, Shaw LJ, Thisted RA, Black HR, Bairey Merz CN, Arnsdorf MF: Heart rate response to exercise stress testing in asymptomatic women: The St. James Women Take Heart Project. Circulation 122, 130-137 (2010). Peak heart rate achieved with exercise in 5437 asymptomatic women submitted to symptom-limited exercise stress testing demonstrated an inverse relationship with increasing age, expressed by 206-0.88(age), which is lower than the traditional estimate of 220-(age). A nomogram was derived. This new formula for estimating peak heart rate during exercise and the derived chronotropic incompetence was found to be a more accurate predictor of all-cause mortality in this study sample.

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Influence of age, gender, and serum triglycerides on heart rate in a cohort of asymptomatic individuals without heart disease

Cited by 8 publications

References 34 publications

Clinical outcomes in acute pancreatitis with relative bradycardia at fever onset

Clinical outcomes in acute pancreatitis with relative bradycardia at fever onset

Under Pressure: The Effect of Antioxidants on Health Consequences Related to Oxidative Stress

Heart Rate Response and Chronotropic Incompetence in Exercise Stress Testing of Asymptomatic Women

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