The results of long-term field research on the search for resistant varieties of bread winter wheat, created at the V. M. Remeslo Myronivka institute of wheat, to major leaf diseases are presented. Researches were performed under conditions of artificial inoculation by pathogens in field infectious nurseries. Varieties with resistance to brown rust have been identified: Kolumbiia, Remeslivna, Pereiaslavka, Bohdana, Monotyp, Khazarka, Pam'iati Remesla, Yasnohirka, Dostatok, Svitanok Myronivs`kyi, Berehynia Myronivs`ka, Horlytsia myronivs`ka, Trudivnytsia Myronivs`ka, MIP Kniazhna, MIP Vyshyvanka. Powdery mildew: Kolumbiia, Remeslivna, Snizhana, Pereiaslavka, Favorytka, Bohdana, Khazarka, Monotyp, Pam'iati Remesla, Voloshkova, Yasnohirka, Lehenda Myronivs`ka, Svitanok Myronivs`kyi, Oberih Myronivs`kyi, Berehynia Myronivs`ka, Horlytsia Myronivs`ka, Hospodynia Myronivs`ka, MIP Valensiia, Trudivnytsia Myronivs`ka, MIP Kniazhna, MIP Vyshyvanka. Common bunt: Kolumbiia, Snizhana, Pereiaslavka, Favorytka, Volodarka, Bohdana, Pyvna, Madiarka, Yuviliar Myronivs`kyi, Myronivs`ka storichna, Yasnohirka, Dostatok, Lehenda Myronivs`ka, Oberih Myronivs`kyi, Berehynia Myronivs`ka, Horlytsia Myronivs`ka, MIP Kniazhna and MIP Vyshyvanka. As well varieties with group resistance to leaf diseases: Kolumbiia, Smuhlianka, Snizhana, Pereiaslavka, Volodarka, Favorytka, Bohdana, Zolotokolosa, Khazarka, Monotyp, Madiarka, Pam'iati Remesla, Lehenda Myronivs`ka, Svitanok Myronivs`kyi, Berehynia Myronivs`ka, MIP Vyshyvanka and varieties MIP Dniprianka, Estafeta Myronivs`ka, Vezha Myronivs`ka.