Influence of Oxygen Saturation, Erythrocyte Concentration and Optical Depth Upon the Red and Near-Infrared Light Transmittance of Whole Blood

Abstract

The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

Fiber Optic Oximetry and Reflexibility of Light by Red Blood Cells

“…The reflected light from blood at 610 my (I ,) will increase as oxyhemoglobin is increased and that at 800 my (Iir) will be constant irrespective of the change in oxygen saturation. Since changes of blood stream (Kuroda and Fujino 1964) or hematocrit (Kramer et al 1951) will cause similar changes on both I, and I,,, Ir/Ir, changes in the same direction as the changes of oxygen saturation irrespective of the alterations of blood stream or hematocrit . Many investigators (Enson et al 1962;Hehir 1962, Gamble et al 1965;Harrison et al 1966) reported that the increase of Ir/Iir was linear to the increase of oxygen saturation, while Mook et al .…”

Spectral imaging of the retina

“…The main absorbing component of human blood is Hb, therefore, its extinction coefficient is assumed to be equal to that of Hb, although this is an approximation as it neglects scattering by the structure of red blood cells. Kramer and Elam 15 were able to demonstrate the linear relationship between the OS of blood and the absorption of red and infrared wavelengths of light. This finding was pivotal in the development of clinical oximeters.…”

The effect of hematocrit on photoelectric plethysmogram.

“…The possibility of hemolysis by adding saline solution for dilution to this blood cannot be neglected. These changes will make influence on the optical effects of the corpuscles (Kramer et al 1951). On the other hand, the peripheral circulation in vivo is formed by a large number of smaller blood vessels, in which the blood does not flow in one direction, but runs in various directions.…”

“…pulse height; propagation time; up-stroke time; model experiment; clinical cases Photoelectric plethysmography is widely used in Japan to evaluate the degree of peripheral vascular disorders, to control the peripheral circulation in pre-and post-operative periods, and to measure the effect of drugs (Nangu 1977). Its principle is based on the amount of light absorption by the hemoglobin content through the tissues (Kramer et al 1951; D'agrosa and Hertzman 1967), which will generate a corresponding degree of electricity. Under such a condition, the pattern of record of toes or fingers is regarded as reflecting the passage of red cells in a given time per tissue.…”