Influence of Poly(lactic acid) Layer on the Physical and Antibacterial Properties of Dry Bacterial Cellulose Sheet for Potential Acute Wound Healing Materials

Foong, Choi Yee; Hamzah, Mohd Syahir Anwar; Razak, Saiful Izwan Abd; Saidin, Syafiqah; Nayan, Nadirul Hasraf Mat

doi:10.1007/s12221-018-7850-7

Cited by 34 publications

(15 citation statements)

References 36 publications

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“…Using a BC/PLA composite, they were able to improve the mechanical properties, maintaining a reasonable wetting time. Also, they observe a preferable surface morphology on a microscopic level (the PLA coating changed into a more fibrous and porous morphology) with a low moisture uptake and prolonged swelling behaviour in simulated environment (Foong et al ., ).…”

Section: Bacterial Cellulose Compositesmentioning

confidence: 97%

“…In most cases, these properties could not be achieved with the isolated base component. The reinforcing phase, which may consist of fibres (Lazarini et al ., ), particles (Galateanu et al ., ), sheets (layers) (Foong et al ., ), interpenetrating networks (Lin et al ., ) or cells, is dispersed in the so‐called matrix or continuous phase (usually the one presenting a higher percentage). The properties of the composites depend on both the nature of the materials employed and the degree of bonding between them through the interface.…”

Section: Bacterial Cellulose Compositesmentioning

confidence: 99%

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Bacterial cellulose: a versatile biopolymer for wound dressing applications

Portela

Leal

Almeida

et al. 2019

Microbial Biotechnology

434

271

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Summary Although several therapeutic approaches are available for wound and burn treatment and much progress has been made in this area, room for improvement still exists, driven by the urgent need of better strategies to accelerate wound healing and recovery, mostly for cases of severe burned patients. Bacterial cellulose (BC) is a biopolymer produced by bacteria with several advantages over vegetal cellulose, such as purity, high porosity, permeability to liquid and gases, elevated water uptake capacity and mechanical robustness. Besides its biocompatibility, BC can be modified in order to acquire antibacterial response and possible local drug delivery features. Due to its intrinsic versatility, BC is the perfect example of a biotechnological response to a clinical problem. In this review, we assess the BC main features and emphasis is given to a specific biomedical application: wound dressings. The production process and the physical–chemical properties that entitle this material to be used as wound dressing namely for burn healing are highlighted. An overview of the most common BC composites and their enhanced properties, in particular physical and biological, is provided, including the different production processes. A particular focus is given to the biochemistry and genetic manipulation of BC. A summary of the current marketed BC‐based wound dressing products is presented, and finally, future perspectives for the usage of BC as wound dressing are foreseen.

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Section: Bacterial Cellulose Compositesmentioning

confidence: 97%

Section: Bacterial Cellulose Compositesmentioning

confidence: 99%

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Portela

Leal

Almeida

et al. 2019

Microbial Biotechnology

434

271

View full text Add to dashboard Cite

show abstract

“…In addition, BC naturally has the capacity to hinder the penetration of bacteria into the tissue, by acting as a physical barrier [ 35 ]. Previously, BC was incorporated with polylactic acid (PLA) and this seemed effective in inhibiting the bacteria invasion, specifically against E. coli and S. aureus [ 86 ]. Apart from this, by reinforcing BC with a dehydrogenative polymer of coniferyl alcohol, AgNP, zinc oxide, gold nanoparticles, and graphene oxide, or with silver nanohybrid and chitosan, this has also been proven to combat bacteria [ 35 ].…”

Section: Characteristics Of Pc and Bcmentioning

confidence: 99%

Plant- vs. Bacterial-Derived Cellulose for Wound Healing: A Review

Naomi

Idrus

Fauzi

2020

IJERPH

119

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Cellulose is a naturally existing element in the plant’s cell wall and in several bacteria. The unique characteristics of bacterial cellulose (BC), such as non-toxicity, biodegradability, hydrophilicity, and biocompatibility, together with the modifiable form of nanocellulose, or the integration with nanoparticles, such as nanosilver (AgNP), all for antibacterial effects, contributes to the extensive usage of BC in wound healing applications. Due to this, BC has gained much demand and attention for therapeutical usage over time, especially in the pharmaceutical industry when compared to plant cellulose (PC). This paper reviews the progress of related research based on in vitro, in vivo, and clinical trials, including the overall information concerning BC and PC production and its mechanisms in wound healing. The physicochemical differences between BC and PC have been clearly summarized in a comparison table. Meanwhile, the latest Food and Drug Administration (FDA) approved BC products in the biomedical field are thoroughly discussed with their applications. The paper concludes on the need for further investigations of BC in the future, in an attempt to make BC an essential wound dressing that has the ability to be marketable in the global marketplace.

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“…57 Coating with poly(lactic acid) (PLA) has been proved to enhance the antibacterial loading capacity and physical properties of BC as graphene oxide did. 80,81 The coated BC/PLA film loaded with benzalkonium chloride (BAC) was found to inhibit the growth of S. aureus and E. coli in a slow and steady release pattern. 82 The exploration into the use of BC in drug delivery systems is deemed to be at an initial stage.…”

Section: Drug Delivery Systemsmentioning

confidence: 99%

Overview of Inexpensive Production Routes of Bacterial Cellulose and Its Applications in Biomedical Engineering

Salihu¹,

Foong²,

Razak³

et al. 2019

Cellulose Chem. Technol.

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Bacterial cellulose (BC) is an innovative polymeric nanofibre, which meets the demands of rapidly advancing industries, such as biomedical engineering, food packaging, pulp and paper and electrical appliance engineering. The versatility of bacterial cellulose is largely due to its unique properties, such as high crystallinity, high thermal stability, high water absorption capacity, hydrophilicity, good mechanical strength, biodegradability, high biocompatibility and high porosity, making it well-suited for applications in various fields. In recent years, advances for enhancing the applicability of BC through modification and its inclusion into composites have been in focus. Unfortunately, despite the multiple advantages it offers, the production cost of BC is too high, thus reducing/limiting its commercial attractiveness and industrial scale production. This paper is an overview of the current research trends for developing cheaper BC production pathways and of recent advances performed so far with the prospect of enhancing its potential application in biomedical engineering.

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Influence of Poly(lactic acid) Layer on the Physical and Antibacterial Properties of Dry Bacterial Cellulose Sheet for Potential Acute Wound Healing Materials

Cited by 34 publications

References 36 publications

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Plant- vs. Bacterial-Derived Cellulose for Wound Healing: A Review

Overview of Inexpensive Production Routes of Bacterial Cellulose and Its Applications in Biomedical Engineering

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