Influence of <scp>UV</scp> filters on the texture profile and efficacy of a cosmetic formulation

Shirata, Marina Mendes Fossa; Campos, Patrícia Maria Berardo Gonçalves Maia

doi:10.1111/ics.12424

Cited by 12 publications

(13 citation statements)

References 14 publications

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“…EP is a mixture of esters formed by the reaction of 2-ethylhexyl alcohol with palmitic acid. It is an important nontoxic raw material typically used as a skin conditioning agent and emollient in cosmetics [24,25] ; however, there is no report of its application in the preparation of MEs. EP could be used to prepare low skin-irritating risk organogels [26] .…”

Section: Analysis Of Diclofenac Sodiummentioning

confidence: 99%

Preparation and Evaluation of O/W and W/O Microemulsions Containing Diclofenac Sodium

Yang¹,

Amnuaikit²,

Boonme³

2021

ijps

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Yang et al.: Diclofenac Sodium MicroemulsionsMicroemulsions are widely used as potential drug delivery systems, especially through the dermal route as a means to avoid systemic side effects. Also, it is well known that the formation and characteristics of MEs depend on their composition. This study aimed to investigate the influence of various types and ratios of components which could dissolve diclofenac sodium on ME formation in term of size of ME regions through the construction of sixteen pseudoternary phase diagrams using the titration method. The data obtained were used to prepare oil-in-water and water-in-oil diclofenac sodium MEs. Two o/w and two w/o blank microemulsions were selected from the system providing the largest ME region and these were subsequently incorporated with 1 % w/w diclofenac sodium. Afterward, their physicochemical and drug release properties were assessed. The largest ME region was found in the system consisting of 2:1 Cremophor RH40:Span 80, ethylhexyl palmitate and 2:1 water:isopropanol. Characteristics of diclofenac sodium MEs were similar to those of their blank counterparts, with the exception of the drug-contained MEs having higher conductivity. Our findings indicated that compatibility of oil and surfactant structures was the crucial parameter for ME formation. Furthermore, the present research not only expanded the phase behavior studies of MEs using different blends of Cremophor RH 40 and Span 80 as surfactant and cosurfactant mixtures, but also reported the application of ethylhexyl palmitate in ME formulations. Incorporation of diclofenac sodium into four studied MEs did not affect ME type. Location of the drug, drug mobility and interfacial film rigidity in MEs were found to influence the release characteristics of the loaded drug.

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Section: Analysis Of Diclofenac Sodiummentioning

confidence: 99%

Preparation and Evaluation of O/W and W/O Microemulsions Containing Diclofenac Sodium

Yang¹,

Amnuaikit²,

Boonme³

2021

ijps

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“…In this context, non‐invasive biophysical and imaging techniques are widely used in studies that evaluate the effects of photoaged skin using in vivo innovative methods that can analyze objectively a wide variety of skin‐related factors, and the correlation of these techniques provides a broad overview of the general characteristics of the skin, besides to contribute to a broad analysis of how photoageing affects the skin as a whole .…”

Section: Introductionmentioning

confidence: 99%

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Shirata

Alves

Campos

2019

Intern J of Cosmetic Sci

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Objectives In view of the lack of studies about the morphological and structural changes caused by solar radiation in young people, the aim of the present study was to evaluate the photoageing‐related changes in the skin of different age groups by biophysical and imaging techniques. Methods Forty‐four healthy female subjects were divided into two age groups: Group 1 (G1): 18–35 years old and Group 2 (G2): 40–60 years old. The skin of malar region of the face was evaluated in terms of mechanical properties, disorder in the pigmentation pattern, morphological and structural changes using the Cutometer®, Colorimeter®, Visioface® and Dermascan C® devices and reflectance confocal microscopy (Vivascope®). Results The results showed that the main changes in the skin of G1 were related to the pigmentation pattern, the papilla format and depletion of thin collagen fibres. These alterations were also observed in the skin of G2, but with more pronounced effects. Conclusion The knowledge about the skin changes caused by photoageing obtained in this study is very important for the development of dermocosmetic products for more effective treatments particularly focused on this type of skin. Finally, objective characterization of photoageing showed the importance of photoprotective habits since the first years of life in order to retard the appearance of skin changes caused by solar radiation.

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“…An emulsion that consists of a mixture of humectants, oils, lipids and others that are essential to maintain skin hydration and smoothness as humectants attract and hold water in the skin and emollients (oils and lipids) occlude and hydrate , and these ingredients are not present on the gel. The improvement touch sensation on gel formulations can be related to the film formation, creating a three‐dimensional network when in contact to the skin, protecting it and improving its texture . Furthermore, the improvement in the white residue in the gel formulations could be related to a better dispersion of the active ingredient in a gel, due to its properties and higher content of water .…”

Section: Resultsmentioning

confidence: 99%

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

Melo¹,

Campos²

2019

Intern J of Cosmetic Sci

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OBJECTIVE: Products with film-forming effect, or 'second skin', which guarantees an immediate protective effect after application, is a highlight, especially when composed of natural ingredients. Thus, the objective of this study was to evaluate the immediate film-forming effect on skin of a gel and emulsion formulations added with Kappaphycus alvarezii and Caesalpinia spinosa extracts through biophysical and skin imaging techniques, especially with the Reflectance Confocal Microscopy (RCM). METHODS: The measurements were done in the forearm region before (baseline) and 1 h after of application of the developed formulation and its control. The parameters related to the stratum corneum water content, transepidermal water loss (TEWL), cutaneous microrelief and morphological and structural characteristics of the epidermis were analysed through the following biophysical and skin imaging techniques: Corneometer â CM 825, Tewameter â TM 300, Visioscan â VC98 and Vivascope â 1500, respectively. A sensorial analysis was also performed to study how the formulations were perceived on the skin. RESULTS: The obtained results showed that the active ingredient under study allows the film formation on the skin surface, leading to a reduction of TEWL and skin desquamation. The obtained

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Influence of UV filters on the texture profile and efficacy of a cosmetic formulation

Cited by 12 publications

References 14 publications

Preparation and Evaluation of O/W and W/O Microemulsions Containing Diclofenac Sodium

Preparation and Evaluation of O/W and W/O Microemulsions Containing Diclofenac Sodium

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

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