Generally, tribology includes three key topics: friction, wear, and lubrication. As humanity progresses, tribology continues to make vital contributions in addressing the demands for advanced technological developments, resulting in increasing machine durability and improving the quality of life. At the point when organic systems particularly human joints for example knees, hips, and so forth which constantly move concerning each other, tribology moves toward becoming bio-tribology. Various essential bio-tribological testing phenomena can significantly influence the result of wear for the implant design and material selection. The study also found the different types of frictional losses in bio-tribology and prevention of these losses. The application of tribology in dentistry is also a growing and rapidly expanding field. In restorative dentistry, metals and alloys and ceramics and composites are generally applied to restorations and implants. The complex inter-oral environment and biomechanics, make the wear processes of artificial dental materials are very complicated and normally include abrasion, attrition, corrosion, fretting wear, and fatigue. These processes occur in various combinations to cause surface loss of materials in the mouth. Intensive research has been conducted to develop an understanding of bio tribology for the successful design and selection of implants and artificial dental materials. This study is carried out to improve the knowledge about bio-tribology and thereby guide the researchers to get their future research directives.