1997
DOI: 10.1016/s0047-6374(97)01889-7
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Influenza (H1N1)–ISCOMs enhance immune responses and protection in aged mice

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Cited by 12 publications
(2 citation statements)
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“…vaccination in DBA/2J mice using live influenza viruses which is very easy to perform because it does not require addition of adjuvants. These results, together with results from other groups [26,27] demonstrate that DBA/2J represents a very sensitive yet fully immuno-competent model system which is well suited to investigate adaptive host immune responses to influenza A virus from bird and human origin without the need for prior species-adaptation.…”
Section: Resultssupporting
confidence: 63%
See 1 more Smart Citation
“…vaccination in DBA/2J mice using live influenza viruses which is very easy to perform because it does not require addition of adjuvants. These results, together with results from other groups [26,27] demonstrate that DBA/2J represents a very sensitive yet fully immuno-competent model system which is well suited to investigate adaptive host immune responses to influenza A virus from bird and human origin without the need for prior species-adaptation.…”
Section: Resultssupporting
confidence: 63%
“…Boon et al showed that sera from humans containing cross-reactive antibodies against pandemic H1N1 virus protected DBA/2J mice from an infection with pandemic H1N1 [15]. Sambhara et al immunized DBA/2J mice by subcutaneous injections with immunostimmulatory complexes containing influenza virus antigens and demonstrated that young and aged mice are better protected than control groups which were immunized with a split vaccine that is used in humans [27]. Solórzano et al, infected the lungs of DBA/2J mice with live-attenuated influenza virus and demonstrated that they are protected from lethal infection with pandemic human H1N1 virus [26].…”
Section: Resultsmentioning
confidence: 99%