DML
 2016
DOI: 10.2174/1872312810666160608123113
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Inhibition of Procarcinogen Activating Enzyme CYP1A2 Activity and Free Radical Formation by Caffeic Acid and its Amide Analogues

Paitoon Narongchai1,
Kanokporn Niwatananun2,
Siripun Narongchai3
et al.

Abstract: From our results, caffeic acid and its amide analogues are in vitro inhibitors of human CYP1A2 catalytic activity and free radical formation. They may be useful to be developed as potential chemopreventive agents that block CYP1A2-mediated chemical carcinogenesis.

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